Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Cdc37"”.
-
Structural and Functional Characterisation of the Nutrient Sensing Kinase GCN2
… the interactions between Hsp90’s co-chaperone Cdc37 and client kinases. These analyses enabled the identification of a correlation between protein stability and dependence on Hsp90/Cdc37, and revealed that Cdc37 binding causes a dramatic conformational remodelling of the N-lobe of the kinase.
-
Analysis of Aurora B Regulation and Signaling
… work. Two molecular chaperones Hsp90 and Cdc37 assist the folding of a variety of kinases in vivo, among which Aurora B is also a candidate. This gave us the final idea of expressing Aurora B-INCENP complexes in bacteria via the coexpression of Hsp90-Cdc37 molecular chaperones.
-
The Development of a Time-Resolved, Vesicle-Based, Fluorescence Assay for the Activity of the Lipid Kinase Pik1
… with both Frq1 and the heat shock protein, Cdc37, producing the Pik1-Frq1 complex with a removable 10xhistidine tag on Pik1. The growth of the yeast transformants was investigated using different culture conditions, media, and methods of inducing protein expression. The expression of the …
-
The Dual Role of OCA-B in B Cell Development and Signaling
… target genes (e.g. Kcnn4, Lck, CyclinD3, and Cdc37) play important roles in cell signaling; however, their specific functions in B cell development and activation are largely unknown. From multiple primary B cell stages, we have found that key OCA-B target genes are expressed and regulated …
-
The role of human and Drosophila NXF proteins in nuclear mRNA export
… in Schneider cells to study the function of Cdc37.