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Showing 1 to 8 of 8 for “"Cdc28"”.

  1. Caractérisation des complexes cycline-Cdc28 impliqués dans la résection des télomères déprotégés chez Saccharomyces cerevisiae

    Korei, MaesumehUniversité de Sherbrooke2015

    … par la principale kinase du cycle cellulaire, Cdc28 (ou Cdk1 pour Cyclin dependant kinase 1), chez Saccharomyces cerevisiae. Par exemple, la déstabilisation des télomères induite par l’inactivation de la protéine Cdc13, une des protéines de la coiffe protectrice du télomère, conduit à la …

    sherbrooke Repository record

  2. An investigation into Cdc28 phosphorylation of Ipl1 and the role of Haspin-like kinases in yeast cell cycle control

    Corbishley, Stephen J.University of Dundee2013

    dundee Repository record

  3. Engineering phosphorylation-dependent post-translational protein devices

    Sutton, Samantha C. (Samantha Carol)Massachusetts Institute of Technology2008

    … and characterize a Phospholocator device, the Cdc28-Phospholocator, whose location is regulated by the activity of cyclin-dependent kinase Cdc28. I next engineered and tested a Fus3-Phospholocator device, whose location is regulated by the activity of the mitogen-activated protein kinase Fus3, …

    mit Repository record

  4. A Genetic and Molecular Analysis of the Control of the Start of the Cell Cycle in Saccharomyces cerevisiae

    Epstein, Charles B

    … the eukaryotic cell cycle is controlled by the CDC28 protein kinase and its homologs. In the budding yeast Saccharomyces cerevisiae, this kinase is required for cell cycle START (commitment to cell cycle progression late in G1), and for entry into mitosis. Although constitutively present, CDC28 …

    rockefeller Repository record

  5. B-cyclin/CDK Regulation of Mitotic Spindle Assembly through Phosphorylation of Kinesin-5 Motors in the Budding Yeast, <italic>Saccharomyces cerevisiae</italic>

    Chee, Mark Kuan Leng2012

    … cerevisiae</italic>, B-type cyclin/CDK (Clb/Cdc28) complexes promote spindle pole separation by inhibiting the degradation of the kinesins-5 Kip1 and Cin8 by the anaphase-promoting complex (APC<super>Cdh1</super>). I have determined, however, that the Kip1 and Cin8 proteins are actually …

    duke Repository record

  6. Functional Genomic Approaches to Study Cell Polarity Regulation by G1 Cyclins in Saccharomyces cerevisiae

    Zou, Jian2010

    … cyclin-dependent kinases (Cdks) Cln1-, Cln2-Cdc28 and Pcl1-, Pcl2-Pho85 are essential for ensuring that DNA replication and cell division are properly linked to cell polarity and bud morphogenesis. However, like most genes in S. cerevisiae, individual cyclin genes are not required for …

    toronto-retro Repository record

  7. Regulation of mitotic spindle biogenesis in budding yeast

    CRASTA KAREN CARMELINA2008

    … and microtubule dynamics. Activation of Cdc28 (Cdk1) by tyrosine-19 dephosphorylation is essential for centrosome separation, the first step in bipolar spindle formation. In this study, we have investigated the regulatory role of Cdk1 in centrosome separation. We show that E3 ubiquitin …

    nus Repository record

  8. Regulation and functions of Cdc14 in mitotic exit in Saccharomyces cerevisiae

    Tomson, Brett NMassachusetts Institute of Technology2009

    … Spol2 phosphorylation is dependent on the CDK, Cdc28, whereas Cdcl4 contributes to the dephosphorylation of Spol2. Lastly, we show that Spol2 phosphorylation is regulated by the FEAR network components Espl and Slk19, but not by the MEN. Overall, this thesis describes research that establishes a …

    mit Repository record