Global ETD Search
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Showing 1 to 4 of 4 for “"Cdc14 release"”.
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Mitotic Exit Control in Budding Yeast: Regulators and Dynamics
<p>In budding yeast, the phosphatase Cdc14 is released from nucleolus to promote mitotic exit (ME). Cdc14 release and ME is controlled by mitotic cyclin-Cdk oscillation, the FEAR network including a non-proteolytic function of separase (Esp1), and the Mitotic Exit Network (MEN) indirectly activated …
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REGULATION OF CHROMOSOME SEGREGATION BY CONSERVED PHOSPHATASE CDC14 AND KINASE CDC5
… from mitosis require the protein phosphatase Cdc14 whose activation relies on two consecutive protein pathways, the FEAR network and the MEN. As the polo-like kinase Cdc5 is a component of both pathways its activity is essential to Cdc14 release and in its absence Cdc14 is never released. By …
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Mechanisms underlying spatial control of exit from mitosis
… In contradiction to these results, I find that Cdc14 release is responsible for the loss of cMT-budneck interactions that precede inappropriate exit from mitosis. Lastly, through the generation of cells with two nuclei, I show that the coupling of spindle position to exit from mitosis is …
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Role of Ame1, a central component of the Saccharomyces cerevisiae kinetochore, in kinetochore function and structure
… of spindle poles occurs in absence of Esp1 and Cdc14 activity. Following experimental evidence suggests that the spindle defect in ame1-2 is not due to the above mentioned causes, but rather results from an alternative function of the kinetochore that is compromised in the mutant in a cell cycle …