Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Cdc13"”.
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Evaluating the role of the fission yeast cyclin B Cdc13 in cell size homeostasis
… concentration with cell size. In fission yeast, Cdc13 (cyclin B), an important activator of the core cell cycle kinase Cdc2 (CDK1), increases in concentration as cells grow. It has been proposed that the concentration of such cell cycle regulators serves as a proxy for cell size and makes cell …
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Caractérisation des complexes cycline-Cdc28 impliqués dans la résection des télomères déprotégés chez Saccharomyces cerevisiae
… induite par l’inactivation de la protéine Cdc13, une des protéines de la coiffe protectrice du télomère, conduit à la résection extensive et non contrôlée des extrémités des chromosomes, promue par la kinase Cdc28. La kinase Cdc28 n’est pas en mesure d’accomplir ses fonctions par elle-même; …
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Biochemical analysis of proteins in the telomere maintenance pathway
… lengthen the DNA after replication. In yeast, Cdc13 recruits either Stn1-Ten1 to form a protective cap or the telomerase holoenzyme to extend the DNA. I have established an in vitro yeast telomere system in which Stn1-Ten1-unextendable or telomerase-extendable states can be observed. Notably, …
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Functional Analysis of the Yku Complex in Telomere Length Regulation
… a novel mutation in the yeast telomerase subunit CDC13/EST4 has been identified earlier in the laboratory. Cdc13p binds to the single stranded DNA overhang at telomeres and is required to recruit the yeast telomerase to chromosome ends. The results presented here suggest that the mutant protein, …