Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Cb2 Agonist"”.
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Characterization of Novel CB2 Agonist SMM-295 and Its Effects in Ischemia/Reperfusion Injury
… our efforts to further categorize the effects of CB2 activation, a possible novel therapeutic target in AKI.</p> <p>There is increasing importance associated with the understanding of the biological activity of the cannabinoid receptors following the increased acceptance in the medicinal purposes …
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THE EFFECT OF A CANNABINOID RECEPTOR 2 (CB2) AGONIST ON ALLERGIC AIRWAY INFLAMMATION IN A MOUSE MODEL OF ASTHMA
… was to explore the anti-inflammatory effects of CB2 agonists on allergic airway inflammation using a mouse model of asthma and resolve any mechanisms that underpin the immunosuppressive properties observed using in vitro assays. The murine model of allergic lung inflammation entailed transferring …
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THE EFFECT OF A CANNABINOID RECEPTOR 2 (CB2) AGONIST ON ALLERGIC AIRWAY INFLAMMATION IN A MOUSE MODEL OF ASTHMA
… was to explore the anti-inflammatory effects of CB2 agonists on allergic airway inflammation using a mouse model of asthma and resolve any mechanisms that underpin the immunosuppressive properties observed using in vitro assays. The murine model of allergic lung inflammation entailed transferring …
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SELECTIVE CB2 RECEPTOR ACTIVATION AMELIORATES INFLAMMATION IN CENTRAL NERVOUS SYSTEM BY REDUCING TH17 CELL DIFFERENTIATION AND IMMUNE CELL ACCUMULATION.
… system by the administration of exogenous agonists and selective antagonists has been shown to have potential to attenuate the contribution of inflammation to secondary injury in the CNS. The two most well-defined receptors are the CB1 and CB2 receptors. CB2, the cannabinoid receptor …
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Studies on the role of the endocannabinoid anandamide, as a possible modulator of events during neointimal formation.
… proliferation revealed that paradoxically both a CB2 agonist and a CB2 antagonist reduced markers of cell proliferation without any effect on cell viability; high concentrations of AEA (10μM) reduced SMC proliferation, however this was associated with an apparent cytotoxic/cytostatic effect. The …
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CANNABINOID RECEPTORS (CB) IN COCHLEA: CHARACTERIZATION AND OTOPROTECTIVE FUNCTIONS
… receptors - CB receptor 1(CB1), CB receptor 2 (CB2) and non CB1 non CB2 types of CB receptor (e.g. GPR, TRPV1) and they belong to G-protein (Gi/o) coupled receptors (GPCR) family.CB1 receptors are abundant in the brain where they modulate neuronal activities. On the other hand, CB2 receptors are …
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Lipid Signaling Under Microgravity Conditions
… JWH-133, a selective cannabinoid receptor 2 (CB2) agonist, in order to determine whether it could reverse the observed changes of inflammatory and functional markers, and thus represent a potential countermeasure to Space-related gastrointestinal dysfunctions.
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Single and Combined Effects of Cannabinoids on Neuropathic Pain and Cognition
… of cannabinoid-based therapies are based on the agonistic action of -9-THC through cannabinoid receptors. Alternatively, some of these effects are caused by the actions of other cannabinoids, like cannabidiol, which does not have high affinity for cannabinoid receptors. Like -9-THC, cannabidiol …
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CANNABINOID RECEPTOR 2 AGONIST REDUCES IMMUNE CELL MIGRATION IN NEUROINFLAMMATION VIA INHIBITION OF MATRIX METALLOPROTEINASE-9
… that administration of cannabinoid receptor agonists in inflammatory/autoimmune and CNS injury models resulted in significant attenuation of clinical disease. The beneficial effects correlated with the observed reduction of inflammatory mediators and peripheral immune cell infiltration into …