Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Cationic porphyrins"”.
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The synthesis of cationic porphyrins for use in photodynamic antimicrobial chemotherapy (PACT
… prior to irradiation was found to be 5 minutes.# Cationic photosensitizers are used in PACT due to their ability to interact with the negatively charged surface of the bacterial cell wall. Several different synthesis were attempted to produce multiply cationic porphyrins.Initially the synthesis of …
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Supramolecular porphyrin arrays on DNA and SWNT scaffolds
… rigid linked monomer. Excitonic coupling of the porphyrins is observed; the different monomers incorporated into DNA show different effects in the circular dichroism spectra, which may be explained through the increased conformational freedom of the ‘flexible’ linker. The synthesis of a novel …
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Synthesis and DNA-binding studies with two stericallyfriendly porphyrin frameworks
<p>Peripheral substituents on cationic porphyrins play a significant role during binding with DNA hosts. Possible applications of these systems in photodynamic therapy as well as in anti-bacterial and anti-cancer therapies motivate the binding studies. For characterizing DNA binding motifs …
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Photoelectrochemical and photophysical studies of carbon nanotube and molybdenum disulfide based light harvesting devices
… were designed using semiconducting SWCNTs and cationic porphyrins as acceptors and donors, respectively. These complexes were assembled by synthetic DNA oligonucleotides that recognize porphyrins, while noncovalently functionalizing SWCNTs. The SWCNT-DNA-porphyrin hybrids were used to …
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PORPHYRIN DERIVATIVES AS VERSATILE PROTEASOME MODULATORS
… drugs available for this use. It is known that cationic porphyrins behave as proteasome inhibitors and their potency depends on the number of positive charges. During this PhD study, we have worked towards a deeper understanding of the molecular mechanisms responsible for the interactions …
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Derivatization of porphyrins for DNA and metal ion binding, especially by employing secondary sulfonamide links
… <p align="justify"> <font size="3" face="Times">Porphyrins are of exceptional importance in nature, science and technology: For instance, as ligands for metals in supramolecular synthesis, as photosenstizers in photodynamic therapy (PDT), and as building blocks for electronic devices. In addition …
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Porphyrin chemistry pertaining to the design of anticancer agents
… that the radio sensitization abilities of the porphyrins might be improved by introduction of certain functional groups (including nitro groups and metal ions), while retaining or improving (by balancing lipophilicity and hydrophilicity) selective properties of porphyrins. Such a drug would …
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Porphyrin Cross-Linkers for Generating Soluble Molecularly Imprinted Polymers from Polyethyleneimine
… <em>meso</em>-substituted, water soluble, tetracationic pyridinium porphyrins which we have successfully coupled to polyethyleneimine (PEI), forming a condensation polyamide. We have demonstrated that one of these porphyrins can be used as an efficient polymer cross-linker, which provides a …