Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Catalepsy"”.
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Behavioral and Electromyographic Comparisons of Neuroleptic and Opiate Catalepsy in Rats
My experiments demonstrate that morphine and haloperidol produce two distinct and contrasting behavioral states, which can be thought of as exaggerated, isolated, and simplified forms of organized adaptive behavioral states functioning as components of normal motivated behavior. Haloperidol ca
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Dopamine D1-Like, D2 and D3 Receptor Subtypes in Catalepsy Sensitization and Conditioning in Rats: Implications for Motor Function, Motivation and Learning
… antagonist haloperidol do not initially exhibit catalepsy, a response quantified by time spent on a horizontal bar without active movement. However, with repeated drug-environment pairings animals show a reduction in exploration and increases in catalepsy. The current thesis examined the …
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Benzodiazepines and Dopamine Mediated Behavior
… behavior and the effects of benzodiazepines on catalepsy and the ventral tegmental area.
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Central Alpha-Adrenoceptors and Behaviour
… head twitches and haloperidol-induced catalepsy. In general, α1 agonists such as methoxamine, had the opposite effect on observed behaviour, producing a syndrome of hyperalertness, hyperalgesia and hyperreactivity which resembled fear. However, high doses did inhibit the pinna reflex …
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Discriminative stimulus properties of 3-substituent rimonabant analogs
… body temperature and produce antinociception and catalepsy. Drugs that produce this tetrad of effects within a limited dose range are likely to function as CB1 receptor agonists. A structure activity relationship study from our laboratory investigating analogs of the CB1 antagonist rimonabant …
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Indagine etnofarmacologica su Casimiroa edulis Llave et Lex
… (like-antidepressant action); it reduced catalepsy haloperidol and PTZ-induced. The extract of bark significantly reduced immobility time in the FST and it increased pentobarbital-induced hypnosis.
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Ruolo dei neurosteroidi nella modulazione dopaminergica
… agents, however, FIN does not elicit catalepsy or other extrapyramidal side-effects. To extend these findings, this thesis is aimed at the assessment of the role of other key neurosteroidogenic enzymes in PPI, such as 17α-hydroxylase/C17,20 lyase (CYP17A1), 3α- and 3β-hydroxysteroid …
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Functional Characterization of CRIP1a Knockout Mice
… to agonist-induced antinociception, hypothermia, catalepsy or motor incoordination did not differ between genotypes. Our findings suggest that CRIP1a could play a selective role in modulation of anxiety by endocannabinoids, and this action could be mediated through the amygdala. Thus, CRIP1a might …
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CYP2D in the Brain Alters Response to Drugs and Neurotoxins
… pretreatment also reduced haloperidol-induced catalepsy in transgenic mice. We demonstrated that CYP2D in rat brain alters brain methamphetamine concentrations and methamphetamine-induced neurotransmitter release and behavioral sensitization. Further, we demonstrated that human CYP2D6 is active …
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The role of stimuli when doing philosophy with children and adults
… the engagement of individuals with it generates catalepsy (a sense of grasping) and moments of epiphany, that can lead to Eros for further inquiry. It is claimed that this is possible when the narrative structure of the stimuli matches with the narrative understanding of the individual when …
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The Role of Connexin36 in Dopamine D1/D2 Synergism and its Breakdown in Transgenic Mice
Most behavioral, physiological and cellular effects of theneurotransmitter dopamine require concomitant activation of both D1 and D2 receptors, a phenomenon referred to as D1/D2 synergism. Since D1 and D2 receptors are located mostly on separate neurons, and since D1/D2 synergism occurs in the …