Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Casein Kinase I"”.
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Casein Kinase I Transduces WNT Signals
… Xenopus embryos. This assay identified a protein kinase, casein kinase I (CKI), as a novel component of the Wnt signaling pathway. We first showed that expression of CKI produces Wnt phenotypes. First, CKI induced completely formed second axes, or Siamese twins, when injected into embryos. Second, …
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Identification of echinus and characterization of its role in Drosophila eye development
… Clathrin, the scaffolding protein RACK1 and the casein kinase I epsilon (Dco). Co-immunoprecipitation additionally identified an interaction between Echinus and Enabled. This work has revealed echinus to be an important regulator of cell sorting and adherens junction formation in the developing …
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Low level Tc1 transposition and Tc1-induced mutations in dpy-5
… presence of a neighbouring gene with homology to casein kinase I.
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Amyloid β Aggregation is Coupled to Cellular Metabolism and Intramitochondrial Proteostasis
… proteins, Ras-like GTP-binding protein rhoA and Casein kinase I isoform alpha, form amyloid structures in a Caenorhabditis elegans model, with ageing. Using this system, we monitor the aggregation of the Amyloid β (1-42) (Aβ42) protein involved in AD, and we show that a new anti-aggregation …
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Studies of Smoothened in Hedgehog Signaling Pathway
… protein Costal2 (Cos2) and a serine/threonine kinase Fused (Fu) form complexes with the transcription factor Cubitus-interrupts (Ci), which is essential for Hh signal transduction. However, how Smo transduces Hh signal to this complex is still not clear. In this study, we found that Smo …