Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 28 for “"Case fatality rate"”.
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Child malnutrition mortality at St Barnabas Hospital is high - is it due to practices and attitudes of staff?: a study in a rural district hospital
The case fatality rate for malnutrition at St Barnabas Hospital over the past years has been around 38%. The rates in other district hospitals in the Eastern Cape province were found to be in excess of 30%. In June 2000, the Eastern Cape Department of Health introduced a protocol for in-patient …
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The production of a Crimean-Congo haemorrhagic fever virus diagnostic antigen in plants
… part of the Bunyaviridae family. CCHFV has a case fatality rate of approximately 40%. Current diagnostic methods for CCHFV involve the use of live virus antigen, requiring biosafety level 4 (BSL4) conditions for safe handling. The development of a safer diagnostic reagent for detection of this …
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Responding to the Pandemic: A Multicountry Study on Social-Political Factors and Health Outcomes of COVID-19
… assess the relationship between democracy and case fatality rate of COVID-19 by controlling for the effect of age, comorbidity, health expenditure, healthcare workforce, and population density; and (3) identify the trajectory pattern cases peak days, deaths peak days, and peak periods.</p> …
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Blood stream infections in oncology patients at Red Cross War Memorial Children's Hospital, Cape Town
… centre studies, 2 systematic reviews and 1 case report. All were observational studies. This literature review showed that BSI is a frequent and important cause of morbidity and mortality in paediatric oncology. Gram-positive bacteria was noted to be the leading type of pathogen causing BSI. …
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Epidemiology of Staphylococcus aureus bacteraemia at a tertiary children's hospital in Cape Town, South Africa
… identified. The annual incidence of SAB was 3.28 cases per 1000 hospital admissions. MRSA was responsible for 26% of SAB and 72% of nosocomial infections. Only six possible cases of community-acquired MRSA infections were described. MSSA bacteraemia was more likely to present as pulmonary and bone …
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Acute Bacterial Meningitis in Zambian children: Highlighting the changing pattern in the Aetiology of Bacterial Meningitis in Zambia
… male to female ratio was 1.2:1, almost 90% of cases came from high density areas of Lusaka. Clinical manifestations ranged from fever with neck stiffness alone, to associated septic shock with petechial rash. The commonest complaints were fever (99%), anorexia (88.5%), headache (73.8%), …
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Acute Bacterial Meningitis in Zambian children: Highlighting the changing pattern in the Aetiology of Bacterial Meningitis in Zambia
… male to female ratio was 1.2:1, almost 90% of cases came from high density areas of Lusaka. Clinical manifestations ranged from fever with neck stiffness alone, to associated septic shock with petechial rash. The commonest complaints were fever (99%), anorexia (88.5%), headache (73.8%), …
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Outcome of Tuberculosis treatment in sputum positive patients after eight months of anti-tuberculosis therapy
… Literature has also revealed an increase in the case fatality rate due to poor diagnosis of TB patients and this is despite TB being a curable and preventable disease. The study is a retrospective audit of Tuberculosis files from January 1997 to December 1997. 256 files of adults who were …
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Outcome of Tuberculosis treatment in sputum positive patients after eight months of anti-tuberculosis therapy
… Literature has also revealed an increase in the case fatality rate due to poor diagnosis of TB patients and this is despite TB being a curable and preventable disease. The study is a retrospective audit of Tuberculosis files from January 1997 to December 1997. 256 files of adults who were …
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Characterization of Flavivirus-Infected Neurons
… can cause severe encephalitis in humans with a case fatality rate as high as 15%. Patients who survived severe encephalitic disease can develop long-term sequelae that can be debilitating and life-long. In this dissertation, a primary human fetal brain neural stem cell system (hNSC) was …
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Scrub typhus: Epidemiology, Diagnosis, Treatment, Prevention and Control in the Asia-Pacific Area and Worldwide
… It can cause severe multiorgan failure with a case fatality rate up to 30% without appropriate treatment. The antigenic heterogeneity of Orientia tsutsugamushi results in reinfection with scrub typhus. As a neglected disease, there is still a large gap in our knowledge of the disease, as …
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Elucidation of Mechanisms of Host Immunity against Orientia tsutsugamushi in a Newly Developed Murine Model
… can cause severe multiorgan failure with a case fatality rate of 7-15%. The current gaps in the knowledge of immunity include the unknown mechanisms of host immunity to O. tsutsugamushi. Using an intravenous (i.v.) disseminated infection mouse model, we observed that more CD8+ T cells than …
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Clinical characteristics, causes, adherence to heart failure treatment guidelines and mortality of patients with acute heart failure: the Groote Schuur Hospital experience
… prevalent (or existing) or incident (or new) cases of heart failure. Results: Of the 119 patients included, 69 (58%) were female and the mean (SD) age was 49.9 (16.3) years. Prevalent cases were mostly of mixed ancestry (63.3%) with more hypertension (70%), diabetes mellitus (36.7%), …
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Trend and factors associated with neonatal mortality among neonates admitted at the women and newborn hospital of the university teaching hospitals, Lusaka, Zambia.
… using a cross-sectional study. The Mortality rates were calculated using WHO standard and Microsoft excel 2010 was used to construct monthly trends analysis using monthly totals. Univariate and multivariate logistic regression analysis was used to determine the factors associated with neonatal …
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Bundibugyo Versus Zaire Ebolaviruses: Examination of the Polymerase Complex as a Therapeutic Target
… EBOV and BDBV are distinctly different in case-fatality rate, disease course, and clinical presentation in both humans and non-human primates, but the reasons for these differences are unknown. Examination of the growth kinetics indicate that variations in the polymerase complex may be a …
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Passive smoking and meningococcal disease
… sixth commonest cause of notified disease with a case fatality rate of 11% for the period 1990 1994. Identification of preventable risk factors is critical as no effective vaccine exists for serogroup B, the most prevalent serogroup in SA. A case control study was undertaken to determine the risk …
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BETACORONAVIRUSES OPTIMIZE REPLICATION BY BALANCING ANTAGONISM OF INNATE IMMUNE RESPONSES AND ER STRESS RESPONSES
… and to identify potential therapeutic strategies, we examined interactions with cellular pathways poised to detect and respond to viral invasion: double-stranded (ds)RNA – a viral replication intermediate - sensing innate immune pathways and endoplasmic reticulum (ER) stress pathways. …
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Characterization of severe and complicated hypertension in Mozambican adults
… with high number of hospitalisations and high case-fatality rate. Moreover, renal damage, stroke and hypertensive heart disease were common complications on follow up. Further research is needed to understand the determinants of these poor outcomes.
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Prevalence and incidence of hypertension and diabetes mellitus in HIV infected persons on HAART in Chongwe district in Lusaka province.
The Zambia National strategic plan (ZNHSP)-2011-2017 highlights the need for risk factor stratification at the community level to form the basis of incidence and prevalence data, which are currently inadequate. This research aims to determine the prevalence and incidence of hypertension and …
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Prevalence and incidence of hypertension and diabetes mellitus in HIV infected persons on HAART in Chongwe district in Lusaka province.
The Zambia National strategic plan (ZNHSP)-2011-2017 highlights the need for risk factor stratification at the community level to form the basis of incidence and prevalence data, which are currently inadequate. This research aims to determine the prevalence and incidence of hypertension and …
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