Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 13 of 13 for “"Cascade reactions"”.
-
Studies toward Augmented Carbene/Alkyne Cascade Reactions and Ruthenium Catalysts for Propargylic Substition
… presents synthetic strategies toward augmented cascade reactions. The second part discusses the synthesis of a ruthenium catalyst and its application for propargylic substitution. The third part describes an improvement of a Robinson annulation for the synthesis of aplykurodinone 1. …
-
One-Pot catalysis and multicomponent cascade reactions for the stereoselective synthesis of Pyrrolidine and indole derivatives
En esta memoria se encuentran recogidos los resultados referidos al estudio de nuevos procesos multicatalíticos en cascada "one-pot" y procesos multicomponente para la síntesis de compuestos heterocíclicos. Esta memoria se ha dividido en dos capítulos. En el Capítulo 1, se describen nuevas síntesis …
-
Designing and optimizing tandem bio- and chemo-catalyzed cascade reactions to access industrially relevant chemicals in mild, aqueous conditions
… Moreover, organocatalysts provide access to reactions and mechanisms similar to enzymatic chemistries with greater stability and fewer restrictions. Taken together, organocatalysts provide a broad reactivity with substrate flexibility and a diverse product profile. These features make …
-
Pushing the limits of aldoxime dehydratases for the synthesis of industrial relevant nitriles and their use in chemo- and biocatalytic cascade reactions
… aldoxime dehydratases in a three-step two-pot cascade reaction. The oxidation of the n-octan-1,8-diol and the condensation with hydroxylamine could be performed in a one-pot two-step sequential reaction and after isolation of n-octanedialdoxime with an isolated yield of 71%, the product was …
-
The Rich Chemistry of Cyclotriveratrylene (CTV) And CT-Inspired Reactions: Anthracenes with Organic Light-Emitting Diode (OLED) Applications and the Discovery of Cascade Reactions
… the chemistry of CTV, we have also discovered cascade reaction sequences, where one reaction sets up the subsequent reaction in a domino fashion, enabling the construction of highly complex molecules in a synthetic single operation. We have discovered that CTV undergoes a dual reaction sequence …
-
Cascade Transformations in Organic Synthesis: I. The Interception of Carbene Alkyne Metathesis Intermediates II. Photo-Activation of Hydrazones III. Organocatalyzed Cascade Conjugate Addition/Aldol Annulation of Organoboronates
This dissertation describes cascade transformations in constructing complex building blocks in synthetic organic chemistry. It includes the interceptions of carbene alkyne metathesis intermediates, boron enolate intermediates, fused cyclopropene intermediates, and boronic acid intermediates. First, …
-
New Methods for the α-Functionalization of Thioesters and Activated Hydrazones and an Application Toward the Total Synthesis of Apratoxin D
<p>Cascade reactions, also referred to as domino reactions, have been widely used for the formation of carbon-carbon bonds. This type of reaction has the potential to circumvent protection and deprotection steps, shortening an overall synthetic process.</p><p>The Morita-Baylis-Hillman (MBH) …
-
Partnering Photochemical Protocols With Anion Relay Chemistry: Application In The Total Synthesis Of Natural Products
… construction paradigm. The development of new cascade reactions via photochemistry is represented in this thesis, in conjunction with the application in the total synthesis of polycyclic natural products. Chapter 2 describes the development of an oxidative Brook rearrangement, achieved by …
-
Biomimetic synthesis of natural products via reactions of ortho-quinone methides
… will describe the use ortho-quinone methides and cascade reactions towards the biomimetic synthesis of the penilactones A and B, the peniphenones A-D, virgatolide B and epicolactone. The total synthesis of ent-penilactone A and penilactone B has been achieved via biomimetic Michael reactions …
-
BIOMEDICAL POTENTIAL OF AMOEBOCYTE LYSATE FROM CARCINOSCORPIUS ROTUNDICAUDA AND TACHYPLEUS GIGAS
… any significant role to play in the gelation cascade reactions. Biochemical similarities between the two types of lysates revealed that a major protein of 21 kDa was involved in the gelation reaction. This protein, later determined to be coagulogen, constitutes approximately 40% of the total …
-
Self assembled transmembrane protein polymer conjugates for the generation of nano thin membranes and micro compartments
… were synthesized. This work aims at carrying out cascade reactions in the Pickering emulsions generated by self assembled enzyme polymer conjugate.
-
Design and engineering of multi-step (bio)catalytic systems
… New in vitro enzymatic or chemoenzymatic cascade reactions need to be designed and optimized to realize stronger synthetic power and more stable systems. Metabolic networks of traditional or new microorganisms should be largely rewired to meet the manufacturing standards. In this work, I …
-
Sustainable biomass-derived hydrothermal carbons for energy applications
… conversion mechanism for cellulose, involving reactions that are commonly observed during pyrolytic processes. The evolution of glucose-derived HTC carbon chemical structure upon pyrolysis was also investigated. These studies revealed that upon heat treatment (Investigated temperatures 350 – …