Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Cartilage injury"”.
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A comparative study of common crosslinking agents for electrospun collagen scaffolds
Cartilage injury is one of the leading causes of knee pain in the world. Over two million Americans suffer from cartilage injury every year, resulting in swelling, pain or joint impairment, causing it difficult to maintain an active life style. Synthetic grafts are used extensively to restore …
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The Effects of Freezing on the Mechanical Properties of Articular Cartilage
… storage methods on the integrity of articular cartilage. Preventing cartilage injury is important in minimizing the long term debilitating effects of osteoarthritis. Accurate subfracture injury prediction must take into account the possible effects that freeze thaw cycles may have on the …
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In vitro models for injurious compression of bovine and human articular cartilage
Patients who have sustained a traumatic joint injury, such as a ligament rupture or cartilage fracture, are known to have an increased risk for the development of osteoarthritis (OA) in that joint. This has motivated the use of in vitro models of mechanical cartilage injury in order to identify …
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Regulation of chondroprogenitor cell gene expression and migration
Cartilage, which lines joint surfaces to allow near-frictionless movement, lacks the ability to adequately repair itself and there are currently no effective, disease-modifying drugs to halt or repair the damage. Development of powerful in vitro models to investigate gene expression changes during …
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In vitro models of cartilage degradation following joint injury : mechanical overload, inflammatory cytokines and therapeutic approaches
… who have sustained an acute traumatic joint injury are at greater risk for the development of OA. The mechanisms by which injury causes cartilage degradation are not fully understood, but the elevated levels of injury-induced pro-inflammatory cytokines, such as TNFa and IL-6, have been …
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Decellularized Cartilage for Airway Repair
… to enlarge the airway by implanting autologous cartilage from a rib graft. However, young children often lack sufficiently sized costal cartilage for this procedure, resulting in increased donor site morbidity and operative time, as well as an elevated risk for airway restenosis, necessitating …
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Application of Cell-Derived Extracellular Matrix (ECM) Scaffold on Tissue Engineering Cartilage
"In recent years, cartilage tissue engineering for reconstruction or repair of a cartilage injury has been emerged as alterative solutions based on the application of selected chondrocytes and scaffold. The purpose of present study is to evaluate the feasibility of novel cell-derived extracellular …