Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 41 for “"Carotid arteries"”.
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Requirements for the detection of atherosclerosis lesions in carotid arteries with SPECT
… we provided procedural guidelines to detect carotid lesions with single photon ,Emission Computed Tomography (SPECT). We first established a method to assess the requirements for "successful" lesion detection. Although this method was used to detect focal carotid lesions, it is also …
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Handedness and the geometry and hemodynamics of the branches of the aortic arch
… and hemodynamic characteristics of the carotid arteries, analysing potential asymmetries between the left and right common, internal and external carotid arteries in leftha-nded versus right-handed individuals. The study is separated into two chapters: geometric (n = 199) and hemodynamic …
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Variations in arterial supply via the external and internal carotid arteries to the bony orbit and eyeball in full-term fetuses, infants, children, adolescents, and adults – a South African perspective
… the ophthalmic artery, a branch of the internal carotid artery, and to a lesser extent by the anastomotic patterns which are formed through the external carotid artery. A range of arterial variations which may be developmental in origin, or which may develop due to pathologies later in life, may …
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Radiomics and Machine Learning in the Prediction of Cardiovascular Disease
Carotid atherosclerosis is a major risk factor for ischaemic stroke which is a leading cause of death worldwide. For stroke survivors, 1 in 4 will have another stroke within five years. Carotid CT angiography (CTA) is commonly performed following an ischaemic stroke or transient ischemic attack to …
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Improved qualification of vascular abnormalities in contrast enhanced magnetic resonance angiographic images
… stroke is the percentage of the narrowing in the carotid arteries, which lead blood from the heart to the brain, which currently is quantified manually. This project is in collaboration with Blackpool Victoria Hospital and Christies Hospital in Manchester. The aim of this project is to develop …
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Stabilised decellularised vascular grafts in an ovine carotid model
… animal (ovine) model. Methods: Porcine mammary arteries were harvested, decellularised according to an established protocol involving rinsing with sodium hydroxide, alcohol (ETOH), treatment with DNAse/RNAse enzymes, immersion in PGG and subsequently surface modified with covalently bound …
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Regulations and functions of P2Y₂ and P2X₇ nucleotide receptors in the central nervous system
… in cerebral ischemia and in collared rabbit carotid arteries. P2Y₂R is up-regulated in response to cytokine stimulation in rPCNs in vitro and after collar transplantation around rabbit carotid arteries in vivo. Moreover, in vivo studies in the collared carotid artery model indicate the …
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Centrinių ir periferinių arterijų struktūrinių ir funkcinių pakitimų ypatumai sergant metaboliniu sindromu /
… and structural changes in cardiovascular arteries and increase of the left ventricle myocardial mass index. The particularity of changes in different arterial stiffness indicators in patients with MS has not been determined yet in the literature, as well as prognostic value of MS when …
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Development of a Passive Immunization Strategy Against Atherosclerosis
… tissue in the wall of medium and large-sized arteries. The characteristic culprit of the disease is the atheroma, or atherosclerotic plaque, a patchy thickening of the arterial wall which affects the lumen, inducing various degrees of stenosis. The rupture of the atherosclerotic plaques, …
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Comprehensive geometric modeling of human cerebral vasculature for quantitative vascular analysis
… anatomical analysis to the anterior cerebral arteries (ACA) and internal carotid arteries (ICA), and characterized their varying size and tortuosity in the cerebral arterial circulation.
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Macrophage Polarization (M1/M2) and its Role in Wnt5a Secretion/Expression in Atherosclerosis
… atherosclerotic tissue sections derived from the carotid arteries of patients undergoing endarterectomy. We also performed immuno-fluorescence analysis to detect Wnt5a in human peripheral blood differentiated M1 and M2 macrophages. </p><p>Our results suggest that Wnt5a secretion/protein expression …
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VEGF and Sympathetic Perivascular Nerves Contribute to Hypoxic Remodeling of Ovine Cranial Arteries
… but not endogenous VEGF level in fetal ovine carotid arteries; 2) both chronic hypoxia and VEGF exert similar effects on smooth muscle contractile proteins; 3) both chronic hypoxia and VEGF exert similar effects on contractile protein colocalizations; and lastly, sympathetic autonomic nerves …
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Functional genomics in the stroke-prone spontaneously hypertensive rat: genome wide and candidate gene analysis
… nitric-oxide bioavailability in SHRSP carotid arteries. Bacterial artificial chromosome and linear expression constructs were purified for production of Gstm1 transgenic rats, putative transgenic rats were screened by PCR. The strategies developed in this project are an example of …
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Central Stimulation of the Vagi and Gastric Secretion
… blood of one dog was perfused into the carotid arteries of a second intact dog. Shortly afterwards, a definite increase in gastric secretion was observed in the intact animal. The effect could be shown to be by way of the vagi, since, following section of the vagal trunk the effect was …
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Relation between carotid artery FDG uptake and cardiovascular risk in asymptomatic adults
We investigated the relation between carotid artery FDG uptake and cardiovascular risk based on the Framingham risk score (FRS), and evaluated the possible role of FDG uptake in terms of risk stratification of asymptomatic adults. We evaluated 290 adults who underwent FDG PET/CT as part of general …
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Occlusion of the Internal Carotid Artery of Horses: Evaluation of a Technique Designed to Prevent Epistaxis Caused by Guttural Pouch Mycosis
… adult horses, the origin of the left internal carotid artery was isolated via a modified hyovertebrotomy approach. Normograde blood flow was occluded by placement of a tourniquet on the artery near its origin. Lumenal access was gained through placement of a distally directed introducer sheath …
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Classification of atherosclerotic plaque vulnerability by mechano-radiomics
… magnetic resonance (MR) images can help evaluate carotid plaque vulnerability better than conventional MR methods. Hemodynamic forces have long been associated with the destabilization of developed plaques near regions of complex blood flow e.g., the carotid bifurcation, which results in high wall …
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Role of SFLT-1 in vascular regulation in pregnancy and its effect on fetal vascular programming
… in response to phenylephrine (PE) in both carotid arteries and uterine arteries, and impaired endothelium-dependent relaxation in uterine arteries of sFlt-1-treated group toward the end of gestation. In addition, pregnant mice over-expressing sFlt-1 displayed a progression toward increased …
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Regulation of the myogenic response and stretch-induced calcium signaling in the vascular wall: Novel insights into the role of microRNAs and protein tyrosine kinase 2
… modulation and apoptosis in balloon injured carotid arteries. In conclusion, we have established an indispensable role of microRNAs in the presssure-induced myogenic response and maintainance of stretch-induced conctractile differentiation. Morover we have established that PYK2 is involved in …
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