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Showing 1 to 6 of 6 for “"Carotid Body"”.
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Transcriptome and Functional Analysis of Carotid Body Glomus Cells
<p>The carotid body (CB) is a major arterial chemoreceptor containing glomus cells that are activated by changes in arterial blood contents including oxygen. Despite significant advancement in the characterization of their physiological properties, our understanding on the underlying molecular …
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Sympathetic control of carotid body excitability in hypertension: A preclinical study
… studies have demonstrated that the integrity of carotid bodies is essential for the development and maintenance of hypertension via exacerbated sympathetic drive. Carotid bodies of spontaneously hypertensive (SH) rats exhibit both hypertonicity and hyperreflexia (i.e., hyper-excitability), which …
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The development and evolution of vertebrate oxygen-sensing cells
… reflex. In the adult, they are located in the carotid body (glomus cells) and lung epithelia (pulmonary neuroendocrine cells) of amniotes, and in the epithelia of the gills and orobranchial cavity (‘neuroepithelial cells’) of anamniotes. Despite their physiological importance, little is known …
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A semiquantitative and qualitative histopathologic assessment of the effect of type II intrauterine growth retardation on the structure of the carotid bodies in fetuses and neonates
The major physiological function of the carotid body is to respond to a low partial pressure of oxygen in the systemic arterial blood. The structure and functions of the adult carotid body have been extensively investigated over the past fifteen years. However, the carotid body in children has been …
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Exploring the molecular mechanisms of AMPK-dependent regulation of neuroexcitability
… channels are critical to oxygen sensing in carotid body type 1 cells, where hypoxia-induced inhibition of TASK-3 and/or TASK-1/3 potassium currents leads to voltage-gated calcium entry, exocytotic transmitter release and increases in carotid body afferent input responses that initiate …
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Unstable Ventilatory Control During Sleep After High Spinal Cord Injury: The Contribution Of Chemosensitivity And Hypoventilation
<p>ABSTRACT</p> <p>UNSTABLE VENTILATORY CONTROL DURING SLEEP AFTER HIGH SPINAL CORD INJURY: THE CONTRIBUTION OF CHEMOSENSITIVITY AND HYPOVENTILATION</p> <p>by</p> <p>Amy T. Bascom</p> <p>May 2015</p> <p>Advisor: Dr. Harry G. Goshgarian</p> <p>Major: Anatomy and Cell Biology</p> <p>Degree: Doctor of …