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Showing 1 to 1 of 1 for “"Carolacton"”.
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NATURAL PRODUCT AND BUILDING BLOCK SYNTHESIS: CAROLACTON-INSPIRED ANALOGS, THE ANTITUMOR THERAPEUTIC FRAX-1036, AND THE CONSTRUCTION OF ATOMICALLY PRECISE MEMBRANES FROM SPIROLIGOMERS
… Sorangium cellulosum, the secondary metabolite carolacton was discovered to be lethal to Streptococcus mutans cells transitioning to the biofilm state. This was a significant finding since S. mutans is the main causative agent of dental caries, the most prevalent chronic childhood and adolescent …