Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Cardiovascular safety"”.
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Market Response to Food and Drug Administration's Safety Warnings: a Case Study Using an Interrupted Time Series Analysis of the Medicare Database for 2006-2008
Objectives: To evaluate the impact of a safety warning on the utilization rates of thiazolidinedione oral anti-diabetes medication using an interrupted time series analysis. Methods: We extracted data from a five percent national sample of Medicare Part D beneficiaries for the periods between …
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Pharmacological modulation of insulin resistance - benefits and harms
… use has been hampered by concerns about their cardiovascular safety, including fluid retention. Metformin is established as first-line glucose-lowering pharmacotherapy in T2DM. It has also been suggested that it may have benefits in alleviating insulin resistance in type 1 diabetes (T1DM). This …
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Toxicities associated with antiretroviral treatment of HIV-1
… and treatment of chronic toxicities such as cardiovascular disease (CVD), metabolic disorders, lipodystrophy, and osteoporosis are essential to ensure patient well being. This thesis aimed to provide more information on these toxicities in two clinical trial settings. Methods: Three …
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The effect of acute intradialytic exercise on cardiovascular responses in hemodialysis patients
… The purpose of this study was to evaluate the safety of IDEX by examining its effect on intradialytic cardiovascular (CV) hemodynamics. Intradialytic changes in brachial, aortic and cardiac hemodynamics and autonomic function were examined during a normal HD session without exercise, or when …
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Concurrent Stimulant and Atypical Antipsychotic Drug Use in Children and Adolescents Diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD)
… and adolescents despite the lack of sufficient safety and efficacy data for such use. Few studies evaluated the concurrent use of stimulant and atypical antipsychotic agents in children and adolescents diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD). Objectives: The goals of this …