Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Cardiometabolic Disorders"”.
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Manganese-enhanced magnetic resonance imaging in cardiometabolic disorders
BACKGROUND AND AIMS: Cardiometabolic disorders include cardiovascular diseases and metabolic conditions such as diabetes mellitus and represent a leading cause of morbidity and mortality worldwide. Identification of specific biological pathways driving progression of these disorders may unveil …
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The Relationship between Cardiometabolic Disorders and Schizophrenia: From Early-Life Origins to the Development of a Cardiometabolic Risk Prediction Algorithm for Young People with Psychosis
… considers the theme of comorbidity between cardiometabolic disorders and schizophrenia by focussing on three key aspects: the nature of association between cardiometabolic disorders and schizophrenia; the potential for common underlying biological mechanisms for the comorbidity; and the …
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Comparison of Anthropometric Measurements of Abdominal Obesity as Predictors of Cardiometabolic Risk Factors: NHANES 2011-2014
… been well established that screening tools for cardiometabolic diseases are less useful among obese populations as risk of these diseases is already high. However, research is lacking in regard to efficient screening tools for cardiometabolic diseases among normal weight and overweight …
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Investigating the Role of Standing Blood Pressure Measurement and the Association Between High-Density Lipoprotein and Skeletal Muscle Mitochondrial Function in Pre-Hypertensive Humans
… mechanisms by which dyslipidemia evoke enhanced cardiometabolic disease risk. Specifically, this dissertation aimed to 1) investigate the role of standing office BP measurement in facilitating HTN diagnosis, and 2) characterize the associations between high-density lipoprotein (HDL) and skeletal …
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Cardiometabolic Diseases and HIV Infection: The Impact of Highly Active Antiretroviral Therapy
… <p> Conclusions: The absolute incidence rate of cardiometabolic disorders and CVD events is not currently higher in HIV infected population compared to general population. However, the risk of CVD may substantially increase with disease progression and use of HAART medications, especially the …
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LARGE-SCALE METAGENOMIC ANALYSIS TO IDENTIFY HUMAN GUT MICROBIOME BIOMARKERS OF CARDIOMETABOLIC HEALTH
… linked with a range of human diseases, including cardiometabolic disorders. Diet is both a well-established determinant of cardiometabolic health and a major factor shaping the gut microbiome, yet many aspects of the diet–microbiome–health axis remain poorly understood, particularly regarding the …
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ROLE OF ASGR1 IN METABOLIC SYNDROME, OBESITY, AND ATHEROSCLEROSIS
… and glycoproteins and lipid metabolism on cardiometabolic disorders such as obesity and atherosclerosis. Methods: Male mice, 2-month-old WT and ASGR1 knockout (ASGR1-/-), were fed with a high-fat diet for 20 weeks (HFD). In those mice, extensive metabolic analysis and immunophenotyping were …
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Characterisation of BMP Processing and Signalling in Adipocytes
… offering new therapeutic avenues for obesity and cardiometabolic disorders.
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Body composition, lung function, blood pressure, and muscular strength: a comparative study
… with or at risk of respiratory diseases and/or cardiometabolic disorders by their total and regional body composition, spirometric, and haemodynamic characteristics may result in more accurate risk stratification, personalised care and effective management strategies, leading to improved …
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INSIGHT ON ANGPTL3 IMPACT ON HEPATIC METABOLISM AND FUNCTION
… resulting into hypolipidemia and protection from cardiometabolic risk. While the role of circulating ANGPTL3 on lipases has been well established, its effect on hepatic homeostasis and metabolism is still unclear. This work aims to unravel the autocrine effects of ANGPTL3 within the liver and its …
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Genomic and metabolomic interrogation of body composition and insulin resistance endotypes
Metabolic syndrome and related cardiometabolic disorders are common yet highly heterogeneous, reflecting different ways in which the complex metabolic interplay among insulin-sensitive tissues can go awry. Current clinical classification remains imprecise, however, relying on broad constructs …