Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Cardiomegaly"”.
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Confirmation of cardiomegaly from the cardiothoracic ratio post-mortem Lodox® imaging
… wall thickening leading to a diagnosis of cardiomegaly. The study was divided into a retrospective component which investigated past use of the CTR (%) in autopsy reports with regards to the cause of death/chief findings, at the Salt River FPS laboratory using the Division of Forensic …
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Acute endomyocardial disease in infants and children : the relationship between acute myocarditis and endocardial fibroelastosis
… failure, gallop rhythm or shock), radiological cardiomegaly (CTR > 0.55), and ST/T wave changes on electrocardiogram (ECG). Acute EMD was confirmed in all 20 patients who came to autopsy. A further 17 patients with insufficient clinical data had EMD at post-mortem.
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The longitudinal outcome of canine myxomatous mitral valve disease in dogs: The LOOK Mitral study
… Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly" (EPIC) trial and left atrial and left ventricular dimensions, assessed by echocardiography, influenced veterinary cardiologist's prescription of cardiovascular drugs in affected dogs. Lastly, we evaluated predictors of reoccurrence of …
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A descriptive study of the use of cardiac point of care ultrasound (PoCUS) in public emergency centres in Cape Town
… dyspnoea,25% (n= 102); chest pain,16%(n=65); cardiomegaly on chest xray,12%(n=51); new murmur,6%(n=23); and chest trauma,5%(n=22). Other indications made up the remaining 10%(n=40). Parasternal long and short axis were the predominantly used views. Conclusion The results of the study suggest …
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Characteristics of cardiovascular dysfunction and pulminory hypertension in patients with sickle cell disease
… that correlated with the<br/>degree of anaemia. Cardiomegaly in SCD patients was not associated with<br/>significant contractile dysfunction as assessed by regional myocardial<br/>deformation. A high proportion (>30%) of SCD patients had a tricuspid<br/>regurgitation jet velocity ! 2.5m/s but …
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FHL2 Inhibits Calcineurin and Represses Pathological Cardiac Hypertrophy
Stress-induced cardiac hypertrophy is a hallmark feature of pathological remodeling which, left unchecked, predisposes hearts to arrhythmia and failure. FHL2 is a member of the four-and-a-half LIM domain (FHL) family of proteins expressed predominantly in the heart. Targeted disruption of FHL2 …
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RalGDS-Dependent Cardiomyocyte Autophagy Is Necessary for Load-Induced Ventricular Hypertrophy
Recent work has demonstrated that autophagy, a phylogenetically conserved, lysosome-mediated pathway of protein degradation, is a key participant in pathological cardiac remodeling. One common feature of cell growth and autophagy is membrane biogenesis and processing. The exocyst, an octomeric …
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The Transcription Factor TFEB Protects Against Cardiac Hypertrophy by Increasing Lysosomal Capacity and Activating AMPKα
Heart failure is one of the leading causes of morbidity and mortality in the modern world. Stress-induced pathological hypertrophy is observed in most forms of heart disease. Pathological cardiac remodeling is a hallmark of impending heart failure. Lysosome-assisted processes such as autophagy and …
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The Effects of Cannabis sativa on the Sperm Epigenome
… to CSE-exposed fathers exhibited significant cardiomegaly relative to those whose fathers were CSE-naïve. Finally, chapter six of this thesis research addressed whether or not the effects of cannabis on human sperm DNA methylation were reversible. Men were recruited to participate in the study …