Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Cardiac progenitors"”.
-
Transcriptional and Translational Regulation of Cardiac Progenitors in the Mouse and Zebrafish
… the heart is the first organ to function and cardiac progenitors are among the first cell lineages to be established. Transcriptional networks control the specification of cardiac progenitors, however, it is not fully understood how some transcription factors function in particular cardiac …
-
PRIMING CARDIOVASCULAR STEM CELLS FOR TRANSPLANTATION USING SHORT-TERM HYPOXIA
… or functional nature in Isl-1+ c-Kit+ human cardiac progenitors are clearly age-dependent. Although both age groups accrued benefit, the neonatal progenitors procured significantly greater improvements. Short-term hypoxia significantly elevated Akt phosphorylation in neonatal Isl-1+ c-Kit+ …
-
MEIS1: At the Crossroads Between Metabolic and Cell Cycle Regulation
… and the subepicardium of the heart as the cardiac hypoxic stem cell niche, which houses a metabolically distinct, Hif-1α positive population of glycolytic cardiac progenitors. Moreover, our studies indicate that Meis1, which regulates HSC metabolism and quiescence, also induces post-natal …
-
miR-322/503 Cluster Drives Cardiac Differentiation by Inhibiting CUG-binding Protein 1
Understanding the mechanisms of early cardiac fate determination may lead to better approaches in promoting heart regeneration after injury. MicroRNAs (miRNAs) involved in the process are particularly interesting due to their small profile and relatively shorter path to clinic. With Mesp1 as the …
-
Zebrafish Cardiac Development Requires a Conserved Secondary Heart Field
… contributes myocardium and smooth muscle to the cardiac arterial pole. This field is part of the overall heart field, and its myocardial component has been fate mapped from the mesoderm to the heart in both mammals and birds. In this study I demonstrate that the population that gives rise to the …