Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"Cardiac magnetic resonance imaging"”.
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Multiparametric cardiac magnetic resonance imaging with motion compensation
Magnetic resonance imaging is a non-invasive imaging modality for the diagnosis of cardiovascular diseases. A broad range of diagnostic parameters can be obtained within a single examination, including information about morphology, physiology and tissue viability. Currently, qualitative …
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Redefinition of uraemic cardiomyopathy with cardiac magnetic resonance imaging
… in LV chamber dimensions. For these reasons, cardiac magnetic resonance imaging (CMR), by providing high fidelity measurements, potentially offers a ‘volume independent’ method of quantifying LV dimensions. Furthermore, by using gadolinium based contrast agents, tissue abnormalities …
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Cardiac magnetic resonance imaging for non-invasive detection of myocardial fibrosis
… the heart muscle, leading ultimately to impaired cardiac function, heart disease and heart failure. Therefore, it is paramount to develop non-invasive technology for the early detection of myocardial fibrosis in order to slow, treat or prevent heart disease and heart failure. Currently, detection …
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Cardiac magnetic resonance imaging assessment of aortic stenosis to improve clinical care
… The aims of this thesis are to investigate novel cardiac magnetic resonance techniques and how they can be applied to improve our decision making around the timing of valve intervention. Methods and Results Cardiac magnetic resonance imaging can detect two forms of myocardial fibrosis …
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High-field Cardiac Magnetic Resonance Imaging in Small Animal Models of Cardiovascular Disease
… when evaluating the efficacy of a potential cardiac therapy. High-field in vivo cardiac magnetic resonance imaging (CMRI) provides high-resolution anatomical images without use of ionizing radiation and is thus uniquely suited to accurately assess the LV and RV. This dissertation reports the …
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Radiofrequency Lesion Assessment by Cardiac Magnetic Resonance Imaging following Atrial Fibrillation Catheter Ablation
… using MRI with gadolinium delayed enhanced (DE) imaging and high signal T2 weighted imaging. Levels of DE and T2 were low in pre-procedural scans but rose dramatically immediately following the procedure. Acute DE was greater in patients without recurrences compared to those with recurrences. …
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Quantification of cardiac magnetic resonance imaging perfusion in the clinical setting at 3T
Dynamic contrast enhanced (DCE) cardiac magnetic resonance imaging (MRI) is well-established as a non-invasive method for qualitatively detecting obstructive coronary artery disease (CAD) which can impair myocardial blood flow and may result in myocardial infarction. Mathematical modelling of …
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Manganese porphyrin for Synthesis of Targeted Contrast Agents for Improving Specificity in Cardiac Magnetic Resonance Imaging
Specificity in imaging narrows our view from the physical anatomy of damaged tissues, to imaging the processes behind it. These are the benefits provided by nuclear medicine in oncology, whose contrast specificity is provided by chelated radionucleotides whose pharmacokinetics are controlled by a …
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New contributions on motion estimation through optical flow techniques applied to cardiac magnetic resonance imaging = Nuevas contribuciones en estimación de movimiento mediante técnicas de flujo óptico aplicado a imagen de resonancia magnética cardiaca
The motion estimation of cardiac tissue and its deformation has been an area of continuous major interest in medical image analysis. Non-invasive estimation of myocardial contractility is of great interest in order to detect regions with abnormal contraction or suspicion of failing arteries, …
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MRI determined tissue characterization of myocardial infiltration and fibrosis in cardiomyopathy
Cardiac Magnetic Resonance Imaging (CMRI) is an important and valuable tool in the routine management of patients with cardiovascular disease. Contrast enhanced CMRI allows detection of ischemic and scarred myocardium, including rare infiltrative processes that cause cardiomyopathies. Amyloidosis …
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Image processing in echography and MRI
… deals with image processing for three medical imaging applications: speckle<br/>detection in 3D ultrasound, left ventricle detection in cardiac magnetic resonance imaging<br/>(MRI) and flow feature visualisation in velocity MRI.<br/><br/>For speckle detection, a learning from data approach was …
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Deep Learning Approach for the Automated Characterization of Cardiac Mechanics
Cardiac mechanics reflects the precise interplay between myocardial structure and contraction essential for sustaining the blood pumping function of the heart. Ejection fraction is the usual index of function, yet mechanical impairment and even heart failure may occur without changes in this …
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Effects of xanthine oxidase inhibitors in pulmonary hypertension associated with chronic lung disease
… in right ventricular mass (RVM) as assessed by cardiac magnetic resonance imaging (CMRI) at twelve months. The secondary outcomes were the change in other cardiac parameters measured by CMRI, St George’s Respiratory Questionnaire, Short Form 36, spirometry and six-minute walk test (6MWT).The …
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Allopurinol Regresses Left Ventricular Hypertrophy in Patients with Type 2 Diabetes.
… in left ventricular mass (LVM) as calculated by cardiac magnetic resonance imaging (CMR) at baseline and at nine months follow-up. The secondary end-points were change in flow mediated dilatation (FMD) and augmentation index (AIx).<br/><br/>Allopurinol significantly reduced absolute LVM (-2.65 ± …
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Adaptive Mechanisms of the Heart to Ischaemic Stress
… physiological measurements and high-resolution cardiac magnetic resonance imaging to assess changes in coronary blood flow, central haemodynamics and transmural myocardial perfusion during exercise. In a separate group, we sought to examine the role of post-conditioning as a potential …
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The effect of allopurinol on left ventricular mass in haemodialysis patients
… session for 1 year. LVMI was assessed by cardiac magnetic resonance imaging (CMR) performed on the post HD day at baseline and after a year of treatment. The secondary outcomes were change in blood pressure (BP), flow mediated dilation (FMD), augmentation indices (Aix) and pulse wave …
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Quantitative and Qualitative Assessment of the Myocardium at Risk
… has been salvaged by the provided treatment. Cardiac magnetic resonance imaging (CMR) has the opportunity to accurately assess both the myocardium at risk as well as the infarct size. This thesis has contributed to the knowledge on quantification of the myocardium at risk and subsequently …
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Dapagliflozin Regresses Left Ventricular Hypertrophy in People with Type 2 Diabetes
… left ventricular mass (LVM), assessed by cardiac magnetic resonance imaging.<br/><br/>In the intention to treat analysis, dapagliflozin significantly reduced LVM compared to placebo with an absolute mean change of -2.82g (95% confidence interval (CI): -5.13 to -0.51, p= 0.018). Additional …
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Biomechanics of Cardiac Remodelling in Heart Failure
Heart failure (HF) occurs when cardiac output does not meet the requirements of the body. HF is the result of maladaptive cardiac remodelling that alters myocardial structure and ventricular function. Current HF treatments were developed targeting patients with systolic dysfunction, but these …
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The Effect of Allopurinol on Left Ventricular Mass in Patients with Treated Essential Hypertension
… the change in left ventricular mass detected by cardiac magnetic resonance imaging (CMRI) from baseline to the final visit. Secondary end-points assessed change in flow mediated dilation, augmentation index, pulse wave velocity, blood pressure control, biomarkers (Urate, High sensitivity …
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