Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Cardiac Biology"”.
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BUBR1 in Cardiac Biology: From Cardiogenesis to Adult Heart Function and Aging
Congenital heart defects and cardiac diseases associated with aging such as heart failure are leading contributors to morbidity and mortality worldwide, yet their underlying molecular mechanisms remain incompletely understood. This dissertation investigates the role of BubR1, a mitotic checkpoint …
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Investigating microRNAs during cardiac development in the chick
… is vital for the complete understanding of cardiac biology. A miRNA expression profile in the chick heart, a model of human heart development, over several stages of embryonic development was generated by next generation sequencing. Two novel chick miRNAs were discovered, and 31 known animal …
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Genetic association of high-dimensional traits
… variants for associations to high-dimensional cardiac phenotypes based on MRI data from 1,500 healthy individuals. I used an unsuper- vised approach to extract a low-dimensional representation of cardiac wall thickness and conducted a GWAS on this representation. In addition, I investigated …