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Showing 1 to 4 of 4 for “"Carcinosarcoma"”.

  1. Identification of Trim24 Domain Essentiality In Primary Trim24Coe Carcinosarcoma Cell Lines

    … these mice revealed over 70% concordance with carcinosarcoma and also were reported to recapitulate human Metaplastic Breast Carcinomas (MpBC).</p> <p>Furthermore, in our earlier research on TRIM24 overexpressing mammary cancer epithelial cell lines, our lab also showed that knocking down …

    uthsc Repository record for Identification of Trim24 Domain Essentiality In Primary Trim24Coe Carcinosarcoma Cell Lines (opens in a new tab)

  2. Trim24 Promotes Mammary Tumor Development By Upregulating Metabolic Reducing Power

    … (<em>Trim24</em><sup>COE</sup>) and develops carcinosarcoma or metaplastic mammary tumors (70% of all <em>Trim24</em><sup>COE</sup> tumors), a rare and aggressive triple-negative subtype called metaplastic TNBC in humans (MpBC). RNA-sequencing revealed that <em>Trim24</em><sup>COE</sup> mouse …

    uthsc Repository record for Trim24 Promotes Mammary Tumor Development By Upregulating Metabolic Reducing Power (opens in a new tab)

  3. Studies in the Folate Metabolism of Rats

    … studied in the rats transplanted with 256 Walker carcinosarcoma. It was concluded that methotrexate inhibits purine biosynthesis by interfering with the steps involving formylfolate. This inhibitory action of methotrexate is in addition to the inhibition of dihydrofolate reductase. In view of …

    aston Repository record for Studies in the Folate Metabolism of Rats (opens in a new tab)

  4. Computational Insights Into The Generation of Chromosomal Copy Number Changes

    … assess tumor heterogeneity of biphasic uterine carcinosarcoma (UCS) from 10 patients by analyzing the data of component-specific tumor samples (carcinomatous, sarcomatous, and normal uterine tissues), generated from multiple platforms (SNP array, DNA target sequencing, and whole transcriptome …

    uthsc Repository record for Computational Insights Into The Generation of Chromosomal Copy Number Changes (opens in a new tab)