Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 118 for “"Carcinoma Cells"”.
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Compressive stress enhances coordinated migration of mammary carcinoma cells
… compressive stress experienced by cancer cells in vivo, we developed an in vitro compression device for compressing a monolayer of cancer cells with precisely-defined normal forces. Here we show, for the first time, that externally-applied compressive stress resulted in faster migration of …
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Identification of Human Adrenal Carcinoma Cells Using Photoacoustic Flow Cytometry
… the absorbance wavelength of human adrenal carcinoma cells, as well as the minimum cell concentration needed in samples using photoacoustic flow cytometry (PAFC). PAFC generates ultrasonic waves when particles under flow absorb laser light. Due to the yellow color in adrenal cancer cells, we …
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Analyzing GFP-tagged cytoskeletal protein colocalization in human carcinoma cells
… culture techniques were used to transfect HeLa cells with four "marker" GFP-tagged protein constructs. Cells were fluorescently labeled in three channels-Hoechst for nucleus, Texas Red phalloidin for actin, and GFP for protein-and images were captured using Cellomics scanning microscopy. After …
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Targeted Differentiation of Primary Head and Neck Squamous Cell Carcinoma Cells
Head and neck squamous cell carcinoma (HNSCC) is a malignant disease; it is the fourth most common cancer in Germany and the sixth most common cancer worldwide, with high fatality rates that have remained essentially unchanged for many years. Especially in the subtype that is negative for human …
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Sonic hedgehog induces Motor Neuron Differentiation in P19 Embryonic Carcinoma Cells
… neuronal differentiation, we utilized embryonal carcinomal P19 cells as an in vitro model system. We overexpressed Shh in P19 cells and investigated it’s effects on proliferation and differentiation of P19 cells., P19/Shh, P19 cells overexpressing Shh, proliferated at higher rates than normal P19 …
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The role of p27 phosphorylation in mediating atRA sensitivity of ovarian carcinoma cells
… shown to inhibit the growth of CAOV3 ovarian carcinoma cells. This results from arrest of the cell cycle during the G1 phase. G1 checkpoint is regulated by a multitude of molecules, including the retinoblastoma family of proteins, cyclin dependent kinases (Cdks), and cyclin dependent kinase …
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Studies of the anti-cancer potential of flavonoids in Human Nasopharyngeal carcinoma cells
… namely luteolin and quercetin on nasopharyngeal carcinoma (NPC) using two NPC cell lines, HK1 and CNE2. We first identified the mechanisms leading to quercetin-mediated cell cycle arrest in NPC cells. Quercetin was able to inhibit E2F-1 transcriptional activity, thus preventing the expression of …
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Radiosensitization of Head & Neck Carcinoma Cells by Linifanib, A Receptor Tyrosine Kinase Inhibitor
… Over 90% of head and neck squamous cell carcinomas (HNSCC) express angiogenic factors such as vascular endothelial growth factor (VEGF). Since radiotherapy is one of the most commonly used treatments for HNSCC, it is imperative to identify the interactions between antiangiogenic therapy …
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Investigation of the functions of Matrix Metalloproteinase-8 (MMP-8) in Mammary Carcinoma Cells
… MMP-8 induced expression of IL-8 in mammary carcinoma cells, and also the expression of a pro-inflammatory cytokine IL-6, dependent on its catalytic activity. This required NFĸB signalling and IL-6 also required Protease Activated receptor-2. This occurred following transient expression of …
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TIS21 shifts p53-induced response of EJ bladder carcinoma cells from senescence to apoptosis
… of thymus, prostate, kidney, and liver. Bladder carcinoma EJ cells contain both oncogenic H-ras and non-functional p53 tumor suppressor due to mutation in its exon 5, possibly contributing to conferring EJ cells cancer characteristic. In normal primary fibroblast cells, over-expression of H-ras …
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NEW PREDICTIVE FACTORS IDENTIFIED BY MOLECULAR STUDY IN CHEMORESISTANT HUMAN AND CANINE MAMMARY CARCINOMA CELLS
… with resistance to chemotherapy in mammary carcinoma cells from dogs and model to human BC. In the first step of this research, five cell lines were used and MDR1, BCRP, MRP1, MRP2 and MRP3 gene expression were assessed to evaluate the baseline expression of these multiple drug resistance …
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Induction of Cellular Induction Senescence by BTG2_(TIS21/PC3) Gene in Huh7 Hepatocellular carcinoma Cells
… senescence of human diploid fibroblast (HDF) cells. Furthermore, when we treated Huh7 hepatoma cells with H₂O₂, the expression of BTG2 mRNA was highly induced, accompanied with senescence phenotypes. To investigate a role of TIS21 in the process of cellular senescence, Huh7 cells were …
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Effects of Oncostatin-M Receptor overexpression on cervical squamous cell carcinoma cells and their extracellular vesicles
Cervical carcinoma remains the fourth most common cause of cancer in women worldwide. Cytological screening and introduction of prophylactic HPV vaccines have drastically decreased incidence rates in high income countries. However, it is still one of the leading causes of cancer morbidity in middle …
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Flower Isoforms Increase Expression in Response to Cellular Stress and Modulate S100 Expression in Cutaneous Squamous Cell Carcinoma Cells
… common cancer in humans, cutaneous squamous cell carcinoma (cSCC), affects more than 1 million patients a year in the United States. cSCC arise from keratinocytes of the epidermis or hair follicles. Current treatments are limited, especially for pre-cancerous lesions. Homeostasis and …
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Studies on the synergic activity of a three-drug cocktail active against cisplatin-resistant human leukemia and carcinoma cells
… complexes previously reported against T-leukemia cells (Pivetta et al.,Talanta, 2013), my research project was aimed at (1) extending the studies of CDDP-Cu(II)-phen combinations as such, as well as with the addition of a third drug component; (2) determining the potential degree of selectivity of …
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The effect of temperature on the bystander effect as examined in human prostate carcinoma cells with alpha particle irradiation
The bystander effect is seen when irradiated cells release a factor that can produce damage or death in neighboring "bystander" cells that are not actually hit by any radiation. One proposed mechanism involves the irradiated cells releasing a soluble factor into the medium that can cause damage to …
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