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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 303 for “"Carboxyl"”.
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Carboxyl Methylation of Non-Histone Chromosomal Proteins
… the methyl groups were esterified to the free carboxyl groups of NHCP since they are heat labile, yielding methanol.</p><p> The carboxyl methylated NHCP from these organs were tightly bound to chromatin. Nucleoplasm and loosely associated NHCP were essentially devoid of methylated protein. …
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Carboxyl terminal truncations of the Phage Mu transposase
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Biology, 1996.
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Biochemical investigation of the ubiquitin carboxyl-terminal hydrolase family
… within and outside the active site of Ubiquitin Carboxyl Terminal Hydrolase (UCH) deubiquinating enzymes (DUBS) help regulate these enzymes interaction with the ubiquitin. I will provide evidence that the putative oxyanion glutamine does function contribute to stabilization of the oxyanion …
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Templated aqueous synthesis of inorganics within carboxyl-containing block copolymer domains
… syntheses of nanoscale inorganic materials in carboxyl-functionalized block copolymer domains (nanoreactors) were demonstrated. First, the successful application of electroless metal deposition within the sub-surface lamellar domains of an amphiphilic block copolymer is presented. Several …
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Optical Characterization of Ultrasmall, Hydrogen -Terminated and Carboxyl -Functionalized Silicon Nanoparticles in Aqueous Environments
… part, three central elements establish that the carboxyl-functionalized Si-np have excellent potential for use as a luminescent marker in aqueous systems. First, they are shown to be ultrasmall, with a diameter of ∼1 nm, comparable to that of common organic fluorophores. Second, they are …
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The Incorporation of Carbon-14 From Carboxyl Labeled Volatile Fatty Acidsinto Goat Liver Glycogen
Made available in DSpace on 2014-12-05T23:08:01Z (GMT). No. of bitstreams: 1 6303221.pdf: 3094852 bytes, checksum: 0e9b25f3f83e8887c0e172334f2cf354 (MD5) Previous issue date: 1962
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Optical Characterization of Ultrasmall, Hydrogen-Terminated and Carboxyl-Functionalized Silicon Nanoparticles in Aqueous Environments
… Si wafer and (2) Chapters 5-6 discuss carboxyl-functionalized Si-np prepared via thermal hydrosilylation of surface Si-H bonds with an ω-ester 1-alkene. Figure 1.1 shows a sketch (based on our results) of an ultrasmall Si-np that is ~1 nm in diameter and contains approximately thirty …
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DegP related proteases in Escherichia coli and carboxyl-terminal tagging of proteins for degradation
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1996.
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Investigating the neuroprotective role of carboxyl-terminus of Hsc70-interacting protein (CHIP) in healthy aging
… and thus are crucial to protein quality control. Carboxyl terminus of Hsp70-interacting protein (CHIP), one such ligase, was initially found to facilitate the polyubiquitination and eventual degradation of aberrantly folded and/or aggregated client proteins in a complex with Hsp70, an essential …
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Small Therapeutic Peptides: In vitro pharmacokinetics of alpha-carboxyl terminus 11 peptide in rat plasma
… they have a very short half-life. Alpha-carboxyl terminus 11 peptide (αCT11) is a 9 amino acid long small peptide that has shown to promote left ventricular function recovery when mouse hearts are perfused with the peptide prior to an ischemia-reperfusion injury. This study investigates …
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The Cx43 Carboxyl-Terminal Mimetic Peptide αCT1 Protects Endothelial Barrier Function in a ZO1 Binding-Competent Manner
The Cx43 CT mimetic peptide, αCT1, originally designed to bind to ZO1 and thereby inhibit Cx43/ZO1 interaction, was used as a tool to probe the role of Cx43/ZO1 association in regulation of epithelial/endothelial barrier function. Using both in vitro and ex vivo methods of barrier function …
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Early calcification patterns of bioprosthetic aortic tissue : a comparison of amino versus carboxyl group and combination cross-linked tissue
Includes bibliographical references.
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Dissecting the Contribution of the Carboxyl-Terminal Domain and Tail of HIV-1 Integrase to Viral Dynamics and Enzymatic Function
… primarily on dissecting the contribution of the carboxyl-terminal domain (CTD), in particular the terminal 18 amino acid 'tail' of this domain, to both the primary integration activities and secondary functions of IN. This was accomplished by conducting a survey of incremental deletions aimed at …
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Characterization of a Putative Activation Domain in the Hulk Gene Family
… including a proline-rich region (PRR) in the carboxyl-terminus. Based on sequence analysis and the presence of a proline-rich domain, it has been suggested that the HULKs are putative transcription factors in which HUA2 is known to regulate several late-flowering genes: FLC, FLM and MAF2. To …
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Synthesis of Labeled 3-Hydroxyproline and Biosynthesis of the Dehydroproline Moiety of Virginiamycin M₁
(R,S)-[Carboxyl-¹⁴C]–cis-3-hydroxyproline was synthesized from S-[carboxyl-¹⁴C] proline. The oxygen functionality at the three position was obtained by acetylation of 1,2-dehydroproline methyl ester using lead tetraacetate. Reduction of the imine with sodium borohydride gave predominately …
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Detailed Analysis of Transcriptional Regulation by Activation Functions-1 and -2 of the Human Estrogen Receptor
… and activation function-2 (AF-2) is near the carboxyl-terminus in the E domain. In most cell and promoter contexts, AF-1 and AF-2 act synergistically to allow full transcriptional activity of ER. Our studies were designed to examine the transcriptional activity of ER and focus on both the …
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Small Phosphomonoesters as Probes of Protein-Tyrosine Phosphatase Active Sites
… of a hydrophobic "handle" to form N-(cyclohexane carboxyl)-O-phospho-L-serine produced a derivative that was hydrolyzed by IphP at rates comparable to that of the avid substrates p-nitrophenyl phosphate and beta-naphthyl phosphate. VHR also hydrolyzed N-(cyclohexane carboxyl)-O-phospho-L-serine, …
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Novel Intermediate Filaments in the Nuclear Envelope: Molecular Cloning and Analysis of Lamins A and C
… exception of an additional 98 amino acid residue carboxyl-terminal tail present only in lamin A and a 6 amino acid residue stretch at the carboxyl terminus of lamin C. The lamin A precursor has a predicted MW of 74 kDa while lamin C has a predicted MW of 65 kDa. The lamins have several structural …
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