Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Carbocations"”.
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Investigating carbocations using high speed ball milling
Carbocations are typically formed in solution, where the solvent stabilizes thecarbocation and mixes the reaction allowing the particles to interact and form products. However, in the absence of solvent it is unknown if the carbocation will form. Previous literature has shown that S<sub>N</sub>2 …
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Synthesis of [beta]-heteroaryl propionates via trapping of carbocations with [pi]-nucleophiles, efforts towards the total synthesis of acutumine, and the design, synthesis, and thermodynamics of protein-ligand interactions at the Src SH2 domain
Heterocyclic alcohols were coupled with [pi]-nucleophiles in the presence of trimethylsilyl trifluoromethanesulfonate to provide a variety of substituted [beta]-heteroaryl propionates, including those with contiguous quaternary centers. This reaction also provided [beta]-heteroaryl propionates …
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Direct Brønsted acid-catalyzed functionalization of benzhydryl alcohols and 2-ethoxytetrahydrofuran using potassium trifluoroborate salts
… alkynyltrifluoroborates and in situ generated carbocations has been developed. In the presence of HBF4, we have shown that organotrifluoroborates react with benzhydryl alcohols to afford alkenes and alkynes in good to excellent yields. This protocol features excellent atom economy since …
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Part I: Development of New Methods for Application in Multicatalytic Reactions Part II: Investigation of Stable Carbenium Catalysts as Hydride Transfer Agents
… of this thesis describes the study of stable carbocations as catalysts for hydride transfer reactions. Both cyclopropenium and trityl catalysts are investigated in a reductive etherification method. A study of trityl catalyst structure and initial investigations into the development of chiral …
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Method Development Towards Catalytic Transformations of Reactive Intermediates
… ortho-quinone methides (o-QMs) and benzylic carbocations, from simple and easily accessed starting materials. The primary goals of each project were to access bioactive material or value added chemicals via the simplest and shortest route possible, limit the toxicity of each component of the …