Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 51 for “"Cannabidiol"”.
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Antibacterial Activities of Cannabidiol Against Two Major Oral Pathogens
… pathogenic biofilm formation on tooth surfaces. Cannabidiol (CBD), a Cannabis sativa L. L. extract, has shown antibacterial properties against various bacterial species, especially gram-positive cocci. This dissertation aimed to evaluate the antibacterial efficacy of CBD against Streptococcus …
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The combined effects of cannabidiol and delta-9-tetrahydrocannabinol
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Studies investigating the mechanisms of the cardioprotective effects of Cannabidiol.
The phytocannabinoid cannabidiol (CBD) has a complex pharmacology which is thought to include, but is not limited to, an ability to act as an inverse agonist at the CB1 and CB2 receptors and an antagonist of GPR55. Moreover, is has been shown to reduce infarct size and ameliorate reductions in left …
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The effects of cannabidiol on measures of performance following eccentric exercise
… a period of time when performance is decreased. Cannabidiol (CBD) is advertised as an anti-inflammatory supplement that can expedite recovery when consumed after exercise. The purpose of this study was to determine if CBD supplementation reduces fatigue and inflammation, and enhances performance, …
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Characterizing the Developmental and Reproductive Toxicities of Cannabidiol and Δ9-Tetrahydrocannabinol
… nineteen states have passed legislation for cannabidiol (CBD) treatment of drug-resistant epilepsy, such as Dravet Syndrome (DS) which is diagnosed in children as young as two months. While CBD has shown anecdotal and recently clinical trial efficacy in reducing seizure frequency in DS …
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The influence of cannabidiol on the effects of delta-9-tetrahydrocannabinol
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Using cannabidiol and trazodone to treat protein misfolding neurodegenerative disease in C. elegans
… In this work, we hypothesized that drug-stacking Cannabidiol and Trazadone, which respectively target ROS production and UPR, would improve the neuronal function and extend the lifespan of neurodegenerative nematode models. To test this hypothesis, we utilized specific strains of C. elegans that …
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Comparison of five oral cannabidiol preparations in adult humans: pharmacokinetics, body composition, and heart rate variability
Data supporting the physiological effects of cannabidiol (CBD) ingestion in humans are conflicting. Differences between CBD preparations and bioavailability may contribute to these discrepancies. Further, an influence of body composition on CBD bioavailability is feasible, but currently …
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Investigating the therapeutic potential of cannabidiol for Alzheimer’s disease: Using Caenorhabditis elegans that express the amyloid-beta protein
… treatments provide limited therapeutic benefits. Cannabidiol (CBD) is a cannabinoid derived from Cannabis plants that has neuroprotective, anti-inflammatory, and antioxidant properties. Research has shown its potential to help decrease Aβ production and protect against Aβ-mediated neurotoxicity in …
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The Effects of Cannabidiol and Analgesic Expectancies on Experimental Pain Reactivity in Healthy Adults: A Balanced Placebo Design Trial
… the effects of analgesic expectancies and cannabidiol (CBD), a non-psychoactive cannabinoid, on human pain reactivity using a balanced placebo design. Despite its frequent use for pain relief, no experimental research has tested the analgesic effects of CBD in humans. Using a …
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THE USE OF PREVENTATIVE CANNABIDIOL, CANNABIGEROL, AND MITRAGYNINE TO AMELIORATE MECHANICAL SENSITIVITY OF PACLITAXEL-INDUCED PERIPHERAL NEUROPATHY IN FEMALE MICE
… have demonstrated the antiallodynic effects of Cannabidiol and Cannabigerol from Cannabis Sativa along with Mitragynine from Mitragyna Speciosa. Not only did they show reduction in mechanical allodynia, but Mitragynine studies showed promise in female-only models. In the present set of …
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Single and Combined Effects of Cannabinoids on Neuropathic Pain and Cognition
… by the actions of other cannabinoids, like cannabidiol, which does not have high affinity for cannabinoid receptors. Like -9-THC, cannabidiol (CBD), the non-psychoactive phytocannabinoid in Cannabis sativa, has been hypothesized to ameliorate adverse effects of -9-THC. Cannabidiol possesses …
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Ampa Receptor Dysregulation And Therapeutic Interventions In A Mouse Model Of Cdkl5 Deficiency Disorder
… drugs, although some patients respond well to cannabidiol. However, underlying mechanisms of what causes hyperexcitability and neurological deficits in CDD is poorly understood. We investigated the novel Cdkl5R59X mouse (R59X), and observed that mutant mice have social interaction and memory …
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An investigation of tetrahydrocannabinol, cannabidiol and cannabinol content of cannabis confiscated by the South African Police Service's Forensic Laboratories from various regions of South Africa
Includes abstract. Includes bibliographical references.
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Estudio de prefactibilidad para la instalación de una planta productora de aceite medicinal
… de Cannabis, en la presentación de 10 mL con 15% Cannabidiol (CBD), es rentable, y la existencia de este producto en el mercado aporta beneficios para la sociedad y permite una mejor calidad de vida considerando la posibilidad del tratamiento de enfermedades como el cáncer, la epilepsia y la …
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ANAESTHESIA AND PAIN MANAGEMENT IN COMPANION ANIMALS
… multimodal pharmacological management involving cannabidiol, a new therapeutic option in dogs affected by osteoarthritis, and the use of radiofrequency, an interventional and non-pharmacological technique, completely new in veterinary medicine. According to the results of our third study, a …
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Cannabinoids and Psychosis – Cause and Treatment
… over sixty cannabinoid molecules, one of which, Cannabidiol (CBD) can antagonise some of the pharmacological effects of THC. It has been suggested that the absence of CBD in modern, 'high-potency' forms of cannabis (sinsemilla or 'skunk') underlies the risk of such preparations for mental health. …
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