Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Candidate Gene Analysis"”.
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A candidate gene analysis of arrhythmogenic right ventricular cardiomyopathy (ARVC)
… loci have been linked to ARVC and six genes have been identified. In 2004 Asano and colleagues reported a mouse model of ARVC that established LAMRI and CBX5 as candidate genes for the human form of ARVC.
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Functional genomics in the stroke-prone spontaneously hypertensive rat: genome wide and candidate gene analysis
… genomic strategies investigated chromosome 2 candidate hypertension genes, focussing on the oxidative-stress defence gene, glutathione s-transferse mu type 1 (Gstm1). Ingenuity pathway analysis of renal microarrays in 5 and 16-week SHRSP, normotensive Wistar Kyoto (WKY) and chromosome 2 …
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Genetics of Obesity and Diabetes in the IRAS Family Study
… concern. Research involving the discovery of genes contributing to these diseases is great public health importance. Identification of a gene and/or genes that contribute to the phenotypic variance of obesity and/or glucose homeostasis traits measured in this study could lead to better methods …
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Understanding the classical maize floral development mutant, Polytypic ear1
… or branch-like protrusions. While the causative gene is unknown, RNA-seq provided direction for candidate gene analysis. Our top candidate gene, ethylene response sensor1 (ers1), encodes a putative ethylene receptor that shows allele-specific expression in Pt1. Ethylene receptors negatively …
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Identifying and dissecting novel QTL regulating seed fatty acid composition in Arabidopsis thaliana for the improvement of rapeseed oil
Genes encoding desaturases in the polyunsaturated fatty acid (PUFA) biochemical pathway have been identified by mutation analyses and utilized in oilseed rape (Brassica napus) breeding programs. However the regulation mechanisms of these genes are as yet unknown and pursued by the oil industry for …
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QTL discovery for Japanese beetle resistance in aphid-resistant germplasm, stacking aphid-resistant genes, and metabolite profiling studies in soybean
… aphid (<Aphis glycines> Matsumura) resistance genes into soybean [<Glycine max >(L.) Merr.] cultivars, it is important to retain resistance to insect defoliators. In order to improve MSU aphid-resistant germplasm for resistance to Japanese beetle (<Popillia japonica> Newman), a population was …
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Investigating the role of host genetic polymorphisms in periodontitis susceptibility in a Western Cape population
… The disease negatively impacts oral and general health, reducing quality of life. Periodontitis management is costly and requires skilled personnel for long-term care, emphasizing the importance of prevention and early diagnosis. Understanding periodontitis pathogenesis involves studying …
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The Genetics of Type 2 Diabetic End-Stage Renal Disease in African Americans
… affected sibling pairs. Following ordered subset analysis (OSA), evidence for linkage was found on chromosomes 3q, 7p, and 18q. On chromosome 18, linkage was observed at 100.5cM in families with an earlier age at diabetes diagnosis (maximized LOD = 3.72; 64% of pedigrees). This region had been …