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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"Candida species"”.
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Sexual Reproduction and Signal Transduction in the Candida Species Complex
… the majority of the population carries <em>Candida spp</em> as normal components of their microflora, these species are important human pathogens that have the ability to cause disease under conditions of immunosuppression or altered host defenses. The spectrum of disease caused by these …
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Salivary carriage of candida species in children and their mothers in a Western Cape population salivary carriage of candida species in children and their mothers in a Western Cape population
Candida albicans has been detected together with Streptococcus mutans in high numbers in children with early childhood caries (ECC). The aim of this study was to explore the prevalence of Candida albicans in children with ECC in the Western Cape, and to explore the possibility of maternal …
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Exploiting Chemical Libraries to Identify and Characterize Novel Bioactives with Efficacy Against Pathogenic Candida Species
Candida species are amongst the most prevalent causes of systemic fungal infections, which account for over 1.5 million annual fatalities. Candida albicans represents the most common etiological agent; however, the rate of infections caused by non-albicans Candida species continues to rise. Here, I …
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Phenotypic and molecular antifungal susceptibility testing of yeast isolates from Pretoria
… the antifungal susceptibility profile of local Candida species and Cryptococcus neoformans isolates and the molecular mechanisms of resistance to different antifungal agents in Pretoria. A total of 250 yeast isolates were collected from the diagnostic laboratory in the Department of Medical …
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Molecular Analysis of Phenotypic Diversity in Human Fungal Pathogens
… conditions experienced in a mammalian host. Candida species can colonize various niches in the human body making them common commensals of the mucosal microbiota, where the maintenance of a stable host-fungus relationship is presumably critical for avoiding disease. However, the importance of …
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A mycological survey of commercial whirlpools in Delaware and Madison counties, Indiana
… of the samples, representing 51%. At least three species of the yeast genus Candid. were isolated from 13 (35%) of these samples. Fifty-eight percent of all dermatophytes isolated were found in male-only whirlpools, as were nearly 62% of all Candida species. Isolated dermatophytes included …
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Perfil epidemiológico das micoses superficiais causadas por leveduras do gênero Candida em laboratório de João Pessoa-PB
… activities undertaken by affected patients. The Candida yeasts have a great importance for the high frequency which colo nize and infect the human host. Candida species are part of the normal flora of the skin, mouth, gastrointestinal tract and genitourinary tract. However, these commensal …
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The Effect of Storage on Activity of Murine Tnf-α: a Comparison of Inbred and Outbred Strains
… genetically homogeneous. The dimorphic yeast, Candida albicans, is an opportunistic pathogen that elicits a macrophage response and subsequent release of TNF-α in both inbred and outbred mice strains. The relationship of this yeast to activity of TNF-α demonstrates the invasiveness of Candida …
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Nanoparticles from microalgae for environmental and biomedical applications
… stability and antifungal activity against Candida species. The research also explores the carbon monoxide oxidizing ability of nanomaterials synthesized from microalgae extracts, presenting diverse Co3O4 catalysts with unique characteristics and improved catalytic performance. Additionally, …
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Dynamics of Agglutinin -Like Sequence (Als) Protein Localization on the Surface of Candida Albicans
… a diverse group of C. albicans strains and other Candida species for the presence of Als proteins or Als-like epitopes. Additionally, Als3 binding to several host proteins proposed to act as ligands for Als3 during C. albicans infection was characterized. Estimation of the number of Als1, Als3, …
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Dynamics of Agglutinin-Like Sequence (Als) Protein Localization on the Surface of Candida Albicans
… a diverse group of C. albicans strains and other Candida species for the presence of Als proteins or Als-like epitopes. Additionally, Als3 binding to several host proteins proposed to act as ligands for Als3 during C. albicans infection was characterized. Estimation of the number of Als1, Als3, …
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Miconazole resistance in fungal biofilms : a molecular point of view
… the activity of miconazole against biofilms of Candida species has been investigated. Furthermore, we have focused on the molecular mechanisms involved in fungal biofilm formation and in resistance to miconazole. The data showed that miconazole has a fungicidal activity against Candida spp. …
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Candida bloodstream infection among children hospitalized in three public sector hospitals in the Metro West region of Cape Town, South Africa
Introduction Candida bloodstream infection (BSI) causes appreciable mortality in children. There are few studies describing the epidemiology of Candida BSI in children living in the Western Cape province of South Africa. Methods A retrospective descriptive study was conducted at three public sector …
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Identification of Effectors of Synergistic Lethality in Candida albicans-Staphylococcus aureus Polymicrobial Intra-abdominal Infection
<p>Candida albicans, an opportunistic fungal pathogen, and Staphylococcus aureus, a ubiquitous pathogenic bacterium, are among the most prevalent causes of nosocomial infections and cause severe morbidity and mortality. Moreover, they are frequently coisolated from central venous catheters and …
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D-arabinitol in the diagnosis of invasive candidiasis
… (DA) and L-arabintiol (LA). Several pathogenic Candida species produce DA in vitro and high DA levels have been detected in serum and urine in patients with IC. Renal dysfunction affects serum DA levels, serum and urine DA/LA or serum DA/creatinine are therefore measured to correct for kidney …
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The role of MK2/TTP pathway in regulating early development and innate immunity in zebrafish
… model infection system for infection by multiple species of Candida, an opportunistic pathogen and cause of an increasing number of hospital acquired infections. I developed novel transgenic zebrafish lines that allow inducible ablation of different phagocyte classes and identified different …
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Discovery and development of novel antifungal agents for the treatment of Candida auris infections
… pathogens responsible for these infections are Candida, Cryptococcus, and Aspergillus. Currently, treatment options for invasive fungal infections are limited to three main classes of antifungal drugs: azoles, polyenes, and echinocandins. The emergence of new fungal species, such as Candida …
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An Investigation into Clinically Relevant Determinants of Azole Resistance in Candida albicans
<p>"Candida albicans is a commensal organism commonly colonizing the human gut and skin. As an opportunistic pathogen, it can cause persistent and serious infections in individuals with compromised immune systems, including the very young and elderly. Moreover, C. albicans can cause a wide spectrum …
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Molecular microbial ecology of hospital ward environments.
… sequences from DNA and RNA templates similar to species associated with human skin and large intestine. While Staphylococci were shown to dominate most environmental sites, Kocuria and Corynebacterium species were found to be specifically associated with the bed rails. Few Gram negative species …
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Targeting Coenzyme A Biosynthesis for Antifungal Development.
… billion in the U.S. alone. Collectively, several Candida species account for more than 75% of disseminated fungal infections in the U.S., with attributable mortality rates ranging 35-75%. Unfortunately, the prospect of curing these infections is limited by the modest efficacy of the available …
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