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Showing 1 to 20 of 234 for “"Candida albicans"”.
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Antigenic Variation in Candida Albicans
… of the germ tube and the yeast phase of Candida albicans have been compared by crossed immunoelectrophoresis, tandem-crossed immunoelectrophoresis and classical immunoelectrophoresis. Qualitative and quantitative differences between the two growth forms have been observed. One unique …
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Factors Governing Gastrointestinal Colonization of Candida albicans
Candida albicans can colonize the human gastrointestinal tract (GI) and cause disseminated infections in immunocompromised hosts. Depletion of specific gut commensal microbiota is associated with or results in increased C. albicans burden in the gut and increased likelihood of dissemination in …
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ERG11-Mediated Azole Resistance in Candida albicans
<p>Although many medically important <em>Candida</em> species are commensal to the gut or colonizers of the skin, these organisms have the propensity to cause disease in the event of a waning immune system. Clinical manifestations of infections with <em>Candida</em> species can range from …
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Studie van het celdoodproces in candida albicans
… 5 is an antimicrobial peptide with potent candidacidal activity present in the saliva of humans. Identification of functions involved in histatin 5-induced cell death can help to resolve the mechanism of action of histatin 5. In order to develop novel antifungal compounds, functions …
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Peering into Candida albicans pir protein function
… was never constructed. Parallel studies in C. albicans indicated the presence of two PIR genes: PIR1 and PIR32. Literature reports suggested allelic variation in the C. albicans PIR genes that was not described for S. cerevisiae, and that deletion of C. albicans PIR1 was a lethal event. The …
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Regulation of The Candida Albicans Arginine Biosynthetic Pathway
<p><em>C</em><em>andida albicans </em>is the most importan thuman-associatedfungus.It is a commensal microorganism but also an opportunistic pathogen able to cause superficial infections aswellaslife-threateninginfectionswhich are associated with a highmortalityrateof 50%. The interactions between …
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Regulation of Alternative Carbon Metabolism In Candida Albicans
<p><em>Candida albicans</em> is the most important fungal pathogen of humans. Transcript profiling studies show that upon phagocytosis by macrophages, <em>C. albicans</em> undergoes a massive metabolic reorganization activating genes involved in alternative carbon metabolism, including the …
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Investigation of Novel Virulence Mechanisms In Candida Albicans
<p><em>Candida albicans </em>is the most important fungal species associated with humans. Normally present in the human microbiome as a commensal colonizer, <em>C. albicans </em>is also the fourth most prevalent organism isolated from bloodstream infections in hospitals. Disseminated infections …
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Adaptation of Candida albicans to Reactive Sulfur Species
The opportunistic fungal pathogen Candida albicans is both a common commensal of the human microbiota and an agent of fatal systemic infections. C. albicans inhabits the mouth and skin, as well as gastrointestinal and genitourinary tracts of humans. One attribute that allows C. albicans to inhabit …
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Repetitive Sequences Drive Rapid Adaptation in Candida albicans
… novel environments. In the human fungal pathogen Candida albicans, genome plasticity resulting in copy number variations (CNVs) and loss of heterozygosity (LOH) confer increased virulence and antifungal drug resistance, yet the mechanisms and dynamics that drive these types of genome plasticity …
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Funktionelle Analysen virulenzrelevanter und essentieller Gene in Candida albicans
… mit dem opportunistisch humanpathogenen Hefepilz Candida albicans, da der Keim, der oftmals als harmloser Kommensale auf den Schleimhäuten im Gastrointestinaltrakt gesunder Menschen vorkommt, vom geschwächten Immunsystem nicht mehr in Schach gehalten werden kann. In dieser Arbeit sollten bestimmte …
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Transcriptional Regulation of Azole Antifungal Resistance in Candida albicans
<p>Candida albicans is a pathogenic fungi found in the mucosa, gastrointestinal, and urogenital tracts of humans. Oropharyngeal candidiasis (OPC), an opportunistic mucosal infection caused by C. albicans, occurs most frequently in patients infected with human immunodeficiency virus (HIV). OPC is …
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Uji efektifitas jamu keputihan terhadap pertumbuhan jamur Candida albicans
… pertumbuhan dan kerusakan dinding sel jamur Candida albicans. Penelitian dilakukan di Laboratorium Mikrobiologi Jurusan Biologi Fakultas Saintek Univesitas Islam Negeri (UIN) Maulana Malik Ibrahim Malang pada Mei sampai Juni 2013. Penelitian ini bersifat eksperimental menggunakan Rancangan …
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Avaliação da atividade antifúngica de fitoconstituintes contra candida albicans
… e infecting patients with immunologic disorders, Candida albicans is the most reported agent causing fungal infections in humans. This fungus is an opportunistic pathogen, which has been found in the human body as a commensal organism, it may become pathog enic as a result of patient’s …
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Drug induced tolerance mechanisms of the fungal pathogen Candida albicans
Candida albicans is a fungal pathogen that already has described mechanisms of resistance. Here we describe mechanisms of drug tolerance.<p></p>
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Alternative Carbon Utilization As A Virulence Determinant For Candida Albicans
<p><em>Candida albicans </em>is a polymorphic unicellular fungus that has evolved to proficiently colonize and infect mammals. A common constituent of the microbiome in the GI tract, mouth, vagina, and skin, <em>C. albicans </em>is also an opportunistic pathogen capable of causing a variety of …
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