Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Cancer--Early detection"”.
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Pancreatic Cancer - Early Detection, Prognostic Factors, and Treatment
Background: Pancreatic cancer is the fourth leading cause of cancer-related death. Only about 6% of patients are alive 5 years after diagnosis. One reason for this low survival rate is that most patients are diagnosed at a late stage, when the tumor has spread to surrounding tissues or distant …
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Breast cancer early detection: A test using hairstylists to promote mammography among women at risk
… among women at risk of developing breast cancer was conducted in Blacksburg, Virginia in the spring of 1989. The intervention employed the theories of planned behavior and diffusion to raise women's intention to seek a mammogram. The study employed a posttest-only control group design and …
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Novel Serum Biomarkers For Lung Cancer Early Diagnosis and Clinical Outcome
… five-year survival rate for all stages of lung cancer combined is only 17%, which has changed little over the past 40 years. Despite the tremendous efforts made, serum biomarkers with clinical utility for lung cancer early detection and clinical outcome prediction are still lacking. Metabolic …
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Development of a Non-Invasive Proteomic Approach to Profiling Molecular Changes in the Microenvironment to Investigate Stages of Breast Health
Early detection of breast cancer is critical for increasing survival rates. However, currently available screening strategies provide ambiguous results, leaving invasive tissue biopsy procedures necessary for definitive diagnosis. Considerable efforts have investigated using nipple aspirate fluid …
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Detecting tumour signals from multi-modal biological features of cell-free DNA fragments
… my work to advance the tumour-naive methods for cancer detection using shallow whole genome sequencing (sWGS) data of cell-free DNA (cfDNA) isolated from plasma. cfDNAs in body fluids inform non-invasive cancer detection. Multimodal Artificial Intelligence (AI) can improve sensitivity by …
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Deep learning on whole-slide images for early detection and risk prediction of oesophageal cancer
… Barrett’s oesophagus (BE), is thus a crucial early detection goal. Identifying the cancer at an early stage drastically increases patient five-year survival to 80%. A new minimally-invasive screening device for BE detection called the Cytosponge presents a solution. Despite this advance, only …
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Defining the Epigenetic Evolutionary Dynamics that Precede Acute Myeloid Leukaemia
Cancer develops over decades before becoming clinically detectable. Understanding this pre-cancerous evolution is crucial for improving the detection, prevention, and treatment of cancer. Previous research has predominantly centred on the somatic and inherited variants which drive cancer. However, …
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Exploration of cell-free DNA’s biological properties for better understanding and improved circulating tumour DNA detection
… techniques that can be used for cancer profiling. Cell-free DNA (cfDNA) are fragmented DNA shed into circulation from various types of cells. The cfDNA derived from cancer cells, circulating tumour DNA (ctDNA), forms a subset of cfDNA. It can be challenging to detect ctDNA as it …
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A qualitative study to critically explore the socio-ecological determinants influencing screening mammography uptake amongst Kerala migrant womenin the United Arab Emirates
… mammography, is effective in detecting breast cancer early enabling better treatment and longer survival. Breast cancer is the most common type of cancer among females in Kerala (India) and is diagnosed at advanced stages of the disease. Keralite women residing in Kerala are less likely to …
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Near real-time early cancer detection using a graphics processing unit
<p>"Automatically detecting early cancer using medical images is challenging, yet very crucial to help save millions of lives in the early stages of cancer. In this work, we improved a method that was originally developed by Yamaguchi et al. from the Saga University in Saga Japan. The original …
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Sensitivity and Specificity of Detecting Premalignant Pancreatic Lesions by Hyperpolarized Magnetic Resonance
<p>Early detection of pancreatic ductal adenocarcinoma (PDAC) is challenging due to asymptomatic nature and deep location of the malignancy within the abdomen. The development of PDAC consists of three different pathways but two arise from the duct, Pancreatic Intraepithelial Neoplasia (PanIN) and …
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Modelo de auditoría para el programa de detección temprana de cáncer de seno en usuarias de una EPS Indígena Activas en el segundo periodo del 2019
El cáncer de seno, una patología con alta tasa de morbi-mortalidad y una enfermedad de alto costo, por lo que nace la necesidad de crear un modelo de auditoría que evalúe y monitorice el impacto del programa “Detección de cáncer de seno” enfocado en las estrategias de tamizaje, seguimiento, …
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Dermato-informatic approaches to understanding and improving lesional diagnostic expertise in cutaneous oncology
… malignancies represent a quarter of all new cancer diagnoses in the UK. The key to reducing the tumours’ associated mortality and morbidity is early diagnosis and treatment. Prompt diagnosis remains predominately a clinical skill, but relatively little investigation of the cognitive …
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Detection of trace levels of circulating tumour DNA in early stage non-small cell lung cancer
… tumour DNA (ctDNA), can detect and quantify cancer in a minimally invasive way and can provide information on tumour heterogeneity. Current limitations in the liquid biopsy field are centred around the general sensitivity of the present assays and the input and logistical requirements for …
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‘A World Where People No Longer Fear Cancer’: An Anthropology of Barrett’s Oesophagus in the UK
… deemed impossible: they have aspired to control cancer. One way in which this has been done is by calculating statistics about cancer risk in ‘populations’, before applying these figures to ‘the individual’. As a result, such individuals may become patients who are eligible for risk management …