Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 263 for “"Cancer Risk"”.
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Calcium metabolism and breast cancer risk
… D and parathyroid hormone (PTH), affect breast cancer risk. The associations between serum calcium levels and breast cancer risk, between serum calcium levels and known risk factors of breast cancer, and between serum calcium levels and breast cancer aggressiveness were examined within the Malmö …
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Exposure, telomere length, and cancer risk
… have repeatedly been associated with increased risk of various types of cancer, as well as with cardiovascular diseases, diabetes, and lung diseases. The aim of this thesis was to explore the effect of exposures on telomere length in different occupational or environmental settings, and also to …
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Tomato Phytochemicals and Prostate Cancer Risk
… of tomatoes that is associated with prostate cancer risk reduction.
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Effects of synbiotics on cancer risk biomarkers
Colorectal cancer (CRC) is the fourth most common cause of death from cancer in the world and second most common (behind lung cancer) in developed countries. In recent years there has been much interest in the potential use of prebiotics, probiotics and synbiotics in the prevention and treatment of …
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Prediction, Communication, and Distribution of Breast Cancer Risk
… group in the United States (US) for which breast cancer is the most frequently diagnosed cancer and leading cause of cancer deaths. Despite the availability of tools to assess breast cancer risk, relatively little is known about the performance of current breast cancer risk prediction models and …
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Life Style, Molecular Pathology, and Breast Cancer Risk
The breast cancer diagnosis covers a wide range of tumours with different geno- and phenotypic characteristics. The diversity among studies on life-style factors and their impact on breast cancer risk might be clarified by recognizing breast cancer as a heterogeneous disease. A major aim of this …
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Advancing Toxicology-Based Cancer Risk Assessment with Informatics
… in the environment from various point sources, cancer risk assessment attempts to define and limit potential exposure such that the risk of developing cancer is negligible. While cancer risk assessment is widely used with certain methodologies well accepted in the scientific literature and …
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Carotenoid metabolism in mice and prostate cancer risk
Prostate cancer is the second most abundant cancer with a 32% mortality rate world-wide. Epidemiological studies suggest an inverse relationship between risk of prostate cancer and intake of tomato products or higher blood levels of lycopene. β-carotene is centrally cleaved by carotene monoxygenase …
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Monogenic, multigenic, and polygenic determinants of cancer risk
A formal series of conditions of lifetime genetic risk of cancer is explored, and algebra is provided for applications in human population genetics. Risks are considered in terms of alleles necessary and/or sufficient for carcinogenesis. Alleles are first classified with respect to their effects on …
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The Complex Association Between Cholesterol Metabolism and Cancer Risk
… of lipid metabolism on other illnesses, such as cancer. This analysis looks at whether there is an association between lipid metabolism parameters (TC, HDL-C, LDL-C) and overall cancer risk as well as the risk of particular cancers such as breast cancer, prostate cancer, and liver cancer. There …
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The microbiota and colon cancer risk: cause or consequence?
Background: Colorectal cancer (CRC) has a complex aetiology involving both genetic and environmental factors. Recently, attention has turned to the influence of the gut microbiota upon the development of CRC. The human gut microbiota is altered in CRC and certain microbial patterns are associated …
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Associations Between Personal Cancer History and Lung Cancer Risk
… relationship between factors related to personal cancer history and lung cancer risk as well as assess their predictive utility. Characteristics of interest included the number, anatomical site(s), and age of onset of previous cancer(s). Data from the Prostate, Lung, Colorectal and Ovarian …
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Microbial pathways of sulfur metabolism and colorectal cancer risk
Colorectal cancer (CRC) is the third leading cause of cancer, and the second leading cause of cancer death in the United States (US). Recent evidence links consumption of a diet high in animal protein and fat as an environmental risk factor for CRC development, and the intestinal microbiota …
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Somatic variation, carcinogenesis and cancer risk in the lung
… loss of functionality and disease. Historically, cancer has been perceived as an evolutionary process involving the continuous acquisition of crucial alterations in a single cell, eventually resulting in its transformation into a cancer cell. However, observing the first changes that occur in …
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Automating comprehensive literature review of cancer risk journal articles
… General Hospital and the Dana Farber Cancer Institute built a calculator that estimates risk of cancer based on genetic mutations. The calculator requires a lot of high quality data from medical journals, which is laborious to obtain by hand. In this thesis, I automate the process of …
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TACTILE AND MULTISPECTRAL BIMODAL IMAGING FOR BREAST CANCER RISK ASSESSMENT
American Cancer Society estimates that in 2021 nearly 300,000 women in the United States will be diagnosed with invasive breast cancer, and about 43,600 women will die from breast cancer. While many have access to health care and cancer screening, women from rural or underdeveloped communities …
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Male Subfertility and Prostate Cancer Risk: Epidemiological and Genetic Studies
… childlessness and prostate cancer (PCa) risk in a nested case-control study to test the hypothesis that subfertile men are at lower risk of developing PCa than fertile men, since they are frequently hypogonadal secondary to testicular dysfunction. Our specific aims were to …
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Bile acid modulation of macrophage phenotype in colorectal cancer risk
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2027-08-01
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Cancer risk prediction with next generation sequencing data using machine learning
… and the strength of the NGS data for the CLL risk prediction.
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