Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Calyx of Held"”.
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The role of auditory sensory input during functional pre- and postsynaptic maturation of the calyx of Held synapse
… nerve activity affects the in-vivo maturation of a fast glutamatergic CNS synapse, the calyx of Held. To address this question we exploited the distinct presynaptic Ca2+ channel subtypes governing transmitter release at the cochlear inner hair cell (IHC)-spinal neuron synaptic junction compared …
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Calcium Triggered Synaptic Vesicle Exocytosis
… triggered by the action potential induced influx of Ca 2+ into nerve terminals. One of the central questions in neuroscience is how Ca 2+ promotes synaptic vesicles from rest to fusion leading to release of neurotransmitters. In this thesis, I first addressed if synaptogmin-1/SNARE binding is …
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Modeling physiological calcium signaling for fast transmitter release at a central synapse : topography of release sites and its functional significance
… in the central nervous system (topography of release sites). The problem, investigated here for the giant synapse calyx of Held, has been addressed before by a number of studies. However, the large number of poorly known parameters has often defeated attempts to conclude which topography …
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Dreidimensionale Rekonstruktion einer exzitatorischen zentralen Synapse : die Held`sche Calyx - Prinzipalneuron Synapse im medialen Nucleus des Trapezkörpers
… die computergestützte 3-D-Rekonstruktion einer Held´schen Calyx - Prinzipalneuron Synapse im medialen Nucleus des Trapezkörpers (MNTB) aus seriellen Ultradünnschnitten einer postnatal Tag 9 alten Ratte. <br>Der Calyx ist eine sehr große (ca. 20-25 µm im Durchmesser) und komplex aufgebaute …
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Functional properties and Ca2+-dependent feedback modulation of voltage-gated Ca2+ channels in glutamatergic nerve terminals of the mammalian auditory brainstem
… im auditorischen Stammhirn der Maus den Heldschen Endbulbs und den Heldschen Calyces durchgeführt. Endbulb-Terminalien zeichnen sich durch einen hohen Eingangswiderstand und eine kleine Membrankapazität aus. Die in Endbulb-Terminalien exprimierten präsynaptischen VGCCs sind überwiegend …