Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Calvarial defect"”.
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Engineering Musculoskeletal Tissue: In vitro and in vivo evaluation of novel scaffolds and growth factors for bone regeneration
… The management of bony non-unions and large bone defects due to congenital deformities, trauma, degenerative disease, and oncological resection remains a complex challenge for orthopaedic surgeons. Currently, autologous bone grafting is the ‘gold standard’ treatment for non-unions and large bone …
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Supporting bone regeneration: Evaluation of endocrine peptides and delivery systems for local application of lactoferrin
… to the site of fracture or other skeletal defects has been recognised as a strategy that could improve healing and lead to better clinical outcomes. Delivery systems that can enhance bone formation, accelerate regeneration and healing, and ultimately restore bone integrity and strength, are …
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Development and evaluation of the innovative 3D printed scaffolds for bone regeneration in vitro and in vivo /
… augmentation is performed by restoring a bone defect with various bone substitutes. However, they fail to match all the ideal bone graft criteria. Therefore, the limitations of existing bone grafting procedures and bone substitutes have led to a strong clinical need to develop and evaluate …
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Biomaterials for bone regeneration
… than straight filament scaffolds in rat calvarial defect at six weeks. Scaffolds with thin (6 ± 1 μm) HA-like surface layers were more effective at stimulating new bone formation, with the curved-filament structures again showing significant improvement in new bone growth compared to the …
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Selective laser sintering of bioactive glass scaffolds and their biological assessment for bone repair
… were evaluated <em>in vivo</em> using a rat calvarial defect model for 6 weeks. Though the results indicated no significant difference in the amount of new bone formation with respect to the defect region, the maturation of the fibrous tissue to bone appeared to be quicker in the scaffolds …
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Layer-by-Layer Systems for Craniomaxillofacial Bone Repair
The treatment of craniomaxillofacial bone defects with drug-eluting synthetic implants is a promising treatment currently being investigated. It is becoming increasingly recognized that release rate of growth factor proteins signaling bone regeneration and vascularization is a key optimization …
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THE EFFECTS OF BONE GRAFTING ON CALVARIAL HEALING IN A RAT MODEL
… model to study non-vascularized and vascularized calvarial grafts; and 2) compare effects o f bone graft vascularity on calvarial healing. Thirty-six rats were divided into Control and Experimental (EXP) groups. Parietal defects were left empty on one side. Contralateral defects in Control, EXP1, …