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Showing 1 to 2 of 2 for “"Calf-2"”.
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Signaling of integrin lower leg and transmembrane domains
… bond to restrict dissociation of the α-subunit Calf-2 domain and β-subunit I-EGF4 domain, we were able to abolish integrin inside-out activation and outside-in signaling. In contrast, disrupting the interface by introducing a glycosylation site into either subunit activated integrins for ligand …
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Mechanisms Of Presynaptic CaV2 Calcium Channel Localization In Caenorhabditis Elegans
… in UNC-2 localization, identifying three genes, calf-1, unc-36 and pqn-53/calf-2. CALF-1 is a neuronal-specific one-pass transmembrane protein that resides in the endoplasmic reticulum, and is required for endoplasmic reticulum exit of UNC-2. Structure-function analysis revealed that the …