Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Calcium dysregulation"”.
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Angiotensin-(1-9) prevents cardiomyocyte hypertrophy via miR-129-3p/PKIA/PKA signaling pathway
… that angiotensin-(1-9) prevents intracellular calcium dysregulation and the activation of Calcineurin/NFAT signaling pathway at a transcription and protein level in a model of norepinephrine-induced cardiomyocyte hypertrophy. To further investigate the anti-hypertrophic mechanism of …
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Role of plasma membrane ATPase4 in the pathophysiology of pulmonary arterial hypertension
… PAH and are known to induce endothelial injury. Calcium dysregulation contributes to apoptotic signalling, suggesting that calcium transporters like Plasma Membrane Calcium ATPase 4 (PMCA4) may play an important regulatory role. PMCA4, encoded by ATP2B4, maintains calcium homeostasis and …
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Neuronal Calcium Regulation and Cellular Stress in a Malignant Hyperthermia Disease Model
<p>Calcium ions (Ca2+) are essential signaling molecules and must be carefully regulated to preserve specificity in function. One indispensible Ca2+ signaling protein is the ryanodine receptor (RyR) calcium release channel. RyR1 is essential for muscle contraction, and RyR1mutations can lead to …