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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 158 for “"Calcium Phosphate"”.
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Degradation of calcium phosphate cements
Contains fulltext : 106967.pdf (Publisher’s version ) (Open Access)
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Osteocapacity of calcium phosphate coatings
Item does not contain fulltext
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Porous calcium phosphate granules for biomedical applications
… repair by integrating them into the host site. Calcium phosphates are used as medical implants because they have a chemical composition similar to the mineral of human bones, i.e. apatite. For this reason they are biocompatible and they can interact in a bioactive way with bone tissue. In the …
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Trabecular Calcium Phosphate Scaffolds for Bone Regeneration
… this research were to develop and characterize calcium phosphate ceramic scaffolds matched to the local architecture of natural trabecular bone and to apply tissue engineering strategies for the study of cell behavior in both in vitro and in vivo models.The specific role of environment on cell …
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Calcium/Phosphate Regulation: A Control Engineering Approach
Calcium (Ca) homeostasis is the maintenance of a stable plasma Ca concentration in the human body in the presence of Ca variability in the physiological environment (e.g. by ingestion and/or excretion). For normal physiological function, the total plasma Ca concentration must be maintained within a …
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Amorphous calcium phosphate nanocomplexes in dental film formulations
… concerns the exploration of novel amorphous calcium phosphate nanocomplexes stabilised by food grade additives. The concept is to generate a formulation to prevent dental caries through enamel remineralisation, supplementing the calcium and phosphate concentrations by delivery from an …
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Amorphous calcium phosphate nanoparticles for biomedical cargo delivery
… presents a potential approach, using amorphous calcium phosphate (ACP) nanoparticles as carriers of organic cargo. ACP is widely used as an in vitro delivery vehicle but similar in vivo use has not been realised. This PhD encompasses development of a practical synthetic route to stable ACP …
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Preclinical evaluation of novel calcium phosphate coated dental implants.
Contains fulltext : 82966.pdf (Publisher’s version ) (Open Access)
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In vitro osteoclast resorption of calcium phosphate bone substitutes
… the in vitro osteoclast (OC) resorption of calcium phosphate (CaP) biomaterials. Resorption of CaP biomaterials is traditionally assessed using an OC resorption assay where resorption pits formed on the CaP surface are analysed by microscopy techniques and quantified on the basis of pit …
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Optimising calcium phosphate cement formulations to widen clinical applications
… drawbacks of autogenous grafts. Since the 1980’s calcium phosphate cements (CPC’s) have attracted a great deal of interest due to their chemical similarities to natural bone; chemical, physical and mechanical characteristics have been investigated and manipulated to maximise osteoconductivity and …
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Osteoblast Response to Zirconia-Hybridized Pyrophosphate Stabilized Amorphous Calcium Phosphate
… sites in vivo. Hydroxyapatite (HAP) and μ-tricalcium phosphate (μ-TCP) ceramics have been incorporated into PLGA bone scaffolds and have been shown to increase their osteoconductivity (support cell attachment). Although HAP, μ-TCP, and biodegradable polyesters are osteoconductive, there is no …
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Magnesium doped calcium phosphate sodium alginate biocomposite for bone implant application
Calcium phosphate (CaP) usually been used for bone implant application due to the similarity mineral in natural bone and it is bioactive and biocompatible material. However, CaP has low mechanical strength under load bearing condition and limited on certain application only. Therefore, sodium …
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Development and assessment of calcium phosphate bone substitutes for orthopaedic applications
… bone is a challenge. Porous scaffolds based on calcium phosphate (CaP) ceramics such as hydroxyapatite (HA) and (3-tricalcium phosphate (P-TCP) have potential in the treatment of injured and diseased bone.<br/><br/>Degradation of CaP’s in vivo occurs as a result of osteoclastic resorption and …
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Application of Calcium Phosphate based gels for encapsulation of therapeutic molecules
… The ultimate aim of this study was to form calcium phosphate (CaP) based matrices as bone grafts for medical applications. Amongst CaP based materials, CaP gels made by the sol-gel process have attracted much interest since they can be processed at room temperature allowing the incorporation …
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Multi-Scale Osteointegration and Neovascularization of Biphasic Calcium Phosphate Bone Scaffolds
Collectively, the thesis demonstrates that (1) the design of synthetic bone scaffolds should include controlled multi-scale porosity to promote multi-scale osteointegration, which may significantly improve scaffold mechanical properties and (2) human umbilical cord blood-derived endothelial colony …
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Antibacterial nanoparticle - decorated carbon nanotube - reinforced calcium phosphate composites as bone implants
Hydroxyapatite (HA) is a biologically active ceramic used in surgery to replace bone. While HA promotes bone growth, it suffers from weak mechanical properties and does not possess any antibacterial property. Multi walled carbon nanotubes (MWCNTs), as one of the strongest and stiffest materials, …
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Calcium Phosphate Nanoparticle Synthesis and Manufacture using Microwave Processing for Biomedical Applications
<p>Calcium phosphate materials (CaP) are known to be major constituents of mammalian bone and synthetic CaPs have been shown to be bioactive in vitro and in vivo. They are one of the most versatile biomaterials for orthopedic applications and have been shown to be effective scaffolds for bone …
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Antimicrobial PLA and Calcium Phosphate Coatings and Thin Film Composites for Implants Applications
Implant-related infections after the insertion of biomedical implants are still prevalent, and the current treatment methodology requires the use of large doses of antibiotics systemically. Large doses can lead to a number of side effects including antibiotic resistance and adverse effects on the …
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