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Showing 1 to 20 of 29 for “"Calcitriol"”.

  1. Knochenanabole Wirkung der zyklischen Calcitriol Therapie

    Nägele, KatrinLudwig-Maximilians-Universität

    … Effekt einer zyklischen Monotherapie mit Calcitriol bei weiblichen SHAM- und OVX-Ratten zu testen. Das Ergebnis der Studie hat gezeigt, dass eine zyklische Monotherapie mit Calcitriol in der Lage ist, die Knochenmasse in einem normalen oder osteopenischen Skelett zu erhöhen und legt nahe, …

    lmu-germany Repository record

  2. Calcitriol Regulation Of Ros 17/2.8 Osteoblast-Like Cell Proteoglycans.

    Waterhous, Therese Storino

    uab Repository record

  3. Evaluación de la actividad antineoplásica de un nuevo análogo del calcitriol

    Ferronato, María Julia2017

    … y la calidad de vida de los pacientes. El calcitriol, la forma activa de la vitamina D3, actúa como una hormona reguladora de la homeostasis fosfocálcica y las investigaciones desarrolladas en las últimas tres décadas avalan su potencial uso como agente antineoplásico en la prevención y …

    uns-ar Repository record

  4. EFFECTS OF 1α,25-DIHYDROXYVITAMIN D3 (CALCITRIOL) ON CULTURED GLIOBLASTOMA MULTIFORME CELLS

    Pinskey, Justine M.2019

    nmu Repository record

  5. SENSITIZATION OF HUMAN OSTEOSARCOMA CELL LINE 143B WITH CALCITRIOL FOR CISPLATIN THERAPY

    Bhamidi Lakshmi, Surya Kameshwari PriyankaUniversity of Kansas2012

    … primary objective is to investigate effects of calcitriol in combination with cisplatin on the osteosarcoma cell apoptosis, invasion and migration. Our hypothesis is pretreatment of OS cells with calcitriol would sensitize them for cisplatin therapy leading to decrease in concentration for IC50. …

    ku Repository record

  6. Efectos del paricalcitol y calcitriol en hiperparatiroidismo secundario en ratas jóvenes con fallo renal

    Mejía Gaviria, Natalia2016

    … de la administración de dosis altas de calcitriol o 1,25 (OH)2 vitamina D3 y al uso de captores de P basados en sales de Ca para el control del HPTs [3]. En un medio urémico, tanto la hiperfosforemia propia de la ERC como la hipercalcemia favorecida por el tratamiento, actúan …

    oviedo Repository record

  7. Einfluss von Steroidhormonen, Calcitriol und Retinolsäure auf die Sekretion proinflammatorischer Zytokine in humanen mononukleären Zellen

    Roßknecht, EvaUniversität Ulm

    ulm-diss Repository record

  8. Characterizing the Development of Secondary Hyperparathyroidism and Vitamin D Resistance in Experimental Chronic Kidney Disease

    Lee, Loky2020

    … renal production of 1,25-dihydroxyvitaminD3 (calcitriol) from its precursor, 25-hydroxyvitaminD3 (calcifediol). Hyperphosphatemia and vitamin D deficiency in CKD stimulate excessive production and secretion of PTH, generating maladaptive consequences to the structure and function of bone and …

    queens Repository record

  9. Effects of vitamin D on pro-inflammatory cytokines associated with Non-alcoholic fatty liver disease

    Ayouk, Nypiat MartinCreighton University2016

    … and cyp27B1 in HepG-2. Treatment of HepG-2s with calcitriol significantly decrease mRNA and protein expression of importin-α3 and attenuate the effects of pro-inflammatory cytokines to induce importin-α3 mRNA and protein expression. IL-10, which is an anti- inflammatory cytokine, significantly …

    creighton Repository record

  10. Síntesis de nuevos análogos del calcitriol (1a, 25-dihidroxivitamina D_3) fósforo funcionalizados : estudio de una nueva metodología para la formación del sistema triénico

    Mascaró, Evangelina2011

    … biológica de EM1, un nuevo tipo de análogo del Calcitriol, forma hormonal de la vitamina D3. EM1 presenta como principales características, una cadena lateral modificada como un alquinilfosfonato que, restringe la libertad conformacional de la misma y limita la acción de la 24-hidroxilasa, …

    uns-ar Repository record

  11. Osteopathie nach orthotoper Herztransplantation

    Ellinger, Marisa ChristineLudwig-Maximilians-Universität

    … Therapie mit dem Vitamin D Metaboliten Calcitriol im Vergleich zu Placebo. Bei Einschluss in die Studie fand sich nur bei 10% der Patienten ein normaler Mineralsalzgehalt im Bereich der LWS, bei 48% ließ sich eine Osteopenie und bei 42% eine Osteoporose nachweisen. Die Rate der …

    lmu-germany Repository record

  12. Vitamin D, ADAM-12 and Carotid Artery Disease

    Kansal, VikashCreighton University2015

    … in presence or absence of IL-6, TNF-α and Calcitriol, in VSMCs was quantified by western blot. HB-EGF release was measured by ELISA. Cell proliferation was assayed by [3H]-Thymidine incorporation and cell counting.|Vitamin D-deficient swine carotid artery VSMCs expressed more ADAM-12, …

    creighton Repository record

  13. Efectos antineoplásicos de nuevos análogos del 1α,25(OH)_2vitamina D_3

    Salomón, Débora Gisele2013

    … nuevos compuestos. El 1α,25(OH)2-vitamina D3 o calcitriol tiene efectos antitumorales en varios tipos de cáncer y algunos ensayos clínicos realizados han dado resultados alentadores, aunque en la mayoría de los casos se ha observado hipercalcemia, lo que dificulta la administración de la dosis …

    uns-ar Repository record

  14. Analysis of Immunomodulatory Effects of Vitamin D in Epithelial-Mesenchymal Transition and Airway Remodeling in Allergic Airway Inflammation.

    Fischer, Kimberly D.Creighton University2015

    … pathogenesis. The active form of vitamin D, calcitriol, exerts its actions through the vitamin D receptor (VDR) inducing a number of biological processes. To better understand the mechanisms underlying EMT and the nature of vitamin D modulation in the airway epithelium, human bronchial …

    creighton Repository record

  15. Towards Identification of Tight Junction Components Involved in the Intestinal Paracellular Absorption of Phosphate

    Radvanyi, Zsuzsa2026

    … Pi handling, it resulted in elevated plasma calcitriol levels but reduced calcitriol responsiveness. Claudin-4 seems to exert cell type-specific effects when depleted or overexpressed in vitro. Conversely, intestine-specific Cldn4 KO mice displayed increased paracellular permeability …

    zurich

  16. Vitamin D and Immunomodulation in Bronchial Asthma

    Agrawal, TanupriyaCreighton University2012

    … adaptive immunity has recently been appreciated. Calcitriol exerts its action through the Vitamin D receptor (VDR), which is a high affinity nuclear receptor. VDR functions as a transcription factor that alters the transcription of target genes involved in a wide spectrum of biological responses. …

    creighton Repository record

  17. The Effects of 1,25-Dihydroxyvitamin D3, Docosahexaenoic Acid and 5-Fluorouracil on Human Breast Cancer Cells

    Engelsen, Liv Astri

    … cell line were treated with 25 μM DHA, 1 μM calcitriol, and 15 μM 5-Fluorourocil alone and in multiple combinations for 72 hours. Both DHA and 5-Fluorouracil slowed growth significantly (p < 0.05). In contrast, vitamin D did not inhibit cell growth at 1 μM. The combination of vitamin D and …

    central-wash Repository record

  18. Ontwikkeling van spirocyclische vitamine D3 analoga met potentiële dissociatie van biologische activiteiten

    De Buysser, Frederik2008

    Since the discovery that 1α,25(OH)2D3 (calcitriol), the hormonally active metabolite of vitamin D3, possesses, next to its classical calciotropic activity, also cell differentiating and antiproliferative activities, there has been a search for analogues in which a dissociation of calcemic and other …

    ghent Repository record

  19. Déploiement et évaluation d’une offre de test de dépistage néonatal pour le rachitisme vitamino-dépendant de type 1A

    Fortin, Carol-AnnUniversité de Sherbrooke2022

    … and tooth enamel hypoplasia. Treatment with calcitriol (Rocaltrol®) restores active vitamin D levels and resolves most of the clinical manifestations mentioned above. However, some consequences persist during adult life, particularly on oral health. Studies have suggested that early treatment …

    sherbrooke Repository record

  20. Relación estructura-actividad de derivados de la vitamina D: síntesis de nuevos análogos, preparación de nanopartículas ORMOSIL conjugadas y evaluación biológica

    González García, Tania2015

    … de la 1alfa,25-dihidroxivitamina D3 (calcitriol), el metabolito más activo de la vitamina D3, la investigación del sistema endocrino de la vitamina D ha recibido una atención creciente. En los últimos años, varios estudios básicos y clínicos muestran nuevos efectos fisiológicos y …

    oviedo Repository record

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