Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 53 for “"Caging"”.
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Caging and Transport in Simple Disordered Systems
… problem motivate reexamining classical models of caging and transport. In particular, seemingly incompatible percolation and mean-field caging descriptions on the localization transition call for better understanding both. In light of this fundamental inconsistency, we study the caging and …
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Interacting Stochastic Processes: from Viciousness to Caging to Force Chains
… while the second, which is due to a caging, or crowding, effect at high densities, appears to be continuous and in a new universality from what is known as conserved directed percolation. The latter transition may have implications for the onset of glassiness in dense, particulate …
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Semi-Synthesis of the Transcription Factor SMAD2 Containing Caging Groups and Phosphoaminoacid Analogues
… of the appropriate wavelength to remove the photocaging group. This approach can be employed to generate caged analogues of any phosphorylated protein. A parallel caging approach was developed that relies upon indirect blockade of Smad2 phospho-dependent activity through the installation of a …
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Caging the Rainbow: The Effects of Center-Periphery Conflict on a Major Adult Education Program in India (Planning, Charisma, Bureaucracy)
In October, 1978, the Government of India launched the National Adult Education Programme (NAEP) for 100 million illiterate adults ages 15 to 35. The program was intended, in five years, to provide 10-month courses in literacy as well as in the development of occupational skills and social …
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Engineering a Photo-Control Mechanism for RNA Interference
… One potential targeting strategy uses photocaging techniques, which involves the covalent attachment of photolabile compounds to the effector NA species that blocks bioactivity until exposed to near UV-light. This work demonstrates that fully-2’-fluorinated nucleic acids (FNAs) can elicit …
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Development and application of chemical tools for investigating dynamic processes in cell migration
… phosphoserine at position 19. The NPE caging group masks the phosphate functionality and inhibits protein function until irradiation at 365 nm releases the native phospho-mRLC to restore myosin activity. Introduction of the caged mRLC into cells enables interrogation of the role of …
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Light-activated gene expression
… The majority of examples employ a classical caging technology, by chemically adding a light-removable protecting group on a biological small molecule of interest and rendering it inactive. The caging group is removed upon UV light irradiation leading to activation of the molecule. The …
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Effects of a polychlorinated biphenyl in mice caged at different densities and fed at different nutritional levels
… if these effects were aggravated by group-caging or feed restriction. The underlying hypothesis was that PCBs may have different physiological effects, dependent on the nutritional status of the animal and the density of the population of which it is a member. The physiological …
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Response of Three Species of Monkeys to Caregiver Use of Species-Typical Behavior
… and body orientation in relation to the front caging, vocalizations, and discrete behaviors. All monkeys showed differences in behavior based on condition. Three monkeys spent significantly more time oriented toward the front caging in the monkey behavior condition. One monkey spent …
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Role of strong attractive forces on the dynamics and mechanics of glass and gel forming soft materials
… the interplay of physical bonding and steric caging. One primary goal is to understand phenomena such as re-entrant solidification, non-monotonic activated structural relaxation, a novel attractive glass state, and small length/time scale ‘in-cage’ dynamical processes. Extension of the new …
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Predation/disturbance effects of greater flamingos (Phoenicopterus ruber) on the benthic communities of two Southern African lagoons
… species showed significant response to caging. Relative to controls, macrofaunal numbers increased approximately three times inside subtidal exclosures, and one and a half times intertidally, but diversity indices were similar between treatments. There was some evidence that amensalistic …
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Comparison of Bare Root vs. Potted Plants, Species Selection, and Caging Types for Restoration of a Prairie Wetland, and Quantitative Analysis and Descriptive Survey of Plant Communities and Associations at Lewisville Lake Environmental Learning Area (LLELA), Lewisville, TX
… for protection, and the success of the different caging was evaluated. Of eight species, only four survived through the second growing season. There was no significant difference in the success of the propagule types for Sagittaria latifolia. The treatments planted with intact root systems showed …
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Synthesis And Biological Evaluation Of Nitrile-Based Inhibitors Of Cysteine Proteases Caged With Ruthenium Complexes
… on developing ruthenium-based photocages for caging nitrile-based cysteine protease inhibitors. Four research areas pertaining to this dissertation, i) metals in medicine, ii) photocages in biological applications, iii) photodynamic therapy and iv) cysteine cathepsin proteases were briefly …
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Tropic interactions within South African intertidal mussel beds
… exposure and shore height and, secondly, field-caging experiments to investigate predation on mussels around the entire coast of South Africa. These two studies allowed for a comparison between predator interactions in the model and in the field.
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The role of quenched disorder, interfaces and confinement on the glassy dynamics of colloidal suspensions, thermal liquids and films
… particle systems are also used to describe caging constraints at solid substrates in supported films. Second, I propose an improved treatment of collective elasticity effects in films to capture geometric asymmetry due to modified boundary conditions. Third, a new theory is constructed for …
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Tumor-Specific STING Agonist Synthesis via a Two-Component Prodrug System
… mild conditions and in complex envi- ronments. Caging one of the reactants with a self-immolative 𝛽-glucuronide moiety resulted in a two-component prodrug system that near-exclusively formed the active compounds in tumors overexpressing 𝛽-glucuronidase. These results exemplify the use of …
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Mapping the synapse : synthesis and validation of chemical probes for interrogating PDZ domains
… elements: solvatochromic fluorophores, molecular caging, and multivalency. This thesis presents the development of a systematic approach to screen for selective solvatochromic fluorophore-based probes for class I PDZ domains, and the biophysical characterization of probes for the PSD-95 and Shank3 …
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Dynamics Of Anisotropic Gold Nanopartilces In Synthetic And Biopolymer Solutions
… the rotation of the rods closely followed the ‘caging theory’.</p>
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Effects of Atrazine on Penned Pheasants and the Occurrence of Stress Marks on Feathers
… to environmental change, limited diet, and caging. Stress marks related to atrazine ingestion were not determinable in the experimental design utilized.
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Caged phosphopeptides and phosphoproteins : probes to dissect the role of phosphorylation in complex signaling pathways
… phase peptide synthesis. Removal of the NPE caging group by irradiation with long-wavelength UV light generates a concentration burst of the corresponding phosphopeptide. In addition, the installation of a caged phosphoamino acid into a full-length, multi-domain protein, the cellular …
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