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Showing 1 to 2 of 2 for “"CaMKK beta"”.
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Regulation of CaMKKβ Dependent Signaling Pathways
… protein kinase kinase β(CaMKKβ) is a serine/threonine directed kinase which is activated following increases in intracellular Ca<super>2+</super>. CaMKKβ activates Ca<super>2+</super>/Calmodulin-dependent protein kinase I (CaMKI), …
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Proteasome Inhibition As A Potential Anti-Breast Cancer Therapy: Mechanisms Of Action And Resistance-Reversing Strategies
… by Calcium/Calmodulin-dependent Kinase Kinase β (CaMKKβ). This hypothesis is supported by pharmacological or genetic inhibition of CaMKKβ that leads to a decrease in proteasome inhibitor-induced AMPK activation. Additionally, the AMPK-activating function of the FDA-approved proteasome inhibitor …