Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Ca2+-activated K+ channel"”.
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Regulation of Ca2+-Activated K+ Channel: Changes with Development
… in response to iberiotoxin, a selective BK channel blocker, is significantly different between adult and fetal VSMCs. Our study of basilar VSMCs in whole-cell preparations showed that the total outward current density of fetal myocytes (57.9 ± 6.7 pA/pF) was greater than that of the adult …
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The role of the large conductance Ca2+-activated K+ channel in adenosine receptor-mediated cytoprotection
… trigger effectors such as the mitochondrial KATP channel – however, the role of the mitochondrial BKCa channel in adenosine receptor-mediated cardioprotection has not been investigated. GPCR assays provided evidence for functional expression of Gi-coupled adenosine A1 and κ-opioid receptors, …
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Intimations on the Development of Effective Treatment for the Prevention of Preterm Birth: β3 Adrenergic Receptor Signaling in the Human Myometrium
… in myometrial endothelial cells, stimulation of Ca2+ activated K+ channel (BKCa), and down regulation of the contractile associated protein connexin 43 (Cx43). The mechanosensitive channel Piezo1 was identified in the myometrium and showed to promote relaxation using similar mechanisms involving …
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T-type Calcium Channels in Arterial Smooth Muscle: Activity, Regulation and Function
Voltage-gated Ca2+ channels (CaV) are key regulators of excitation-contraction coupling in arterial smooth muscle. Despite evidence of T-type CaV channels in rodent smooth muscle, little is known of their regulation and function. This thesis sought to delineate T-type Ca2+ channels, ascertain if …
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Activation of Ca<sup>2+</sup>-activated K<sup>+</sup> Channels and Cell Migration by Hepatocyte Growth Factor/Scatter Factor in Madin-Darby Canine Kidney Cells.
… of a charybdotoxin (ChTX)-sensitive, volume-activated membrane K<sup>+</sup> current. Patch-clamp electrophysiology and transwell migration assays were used to study the effects of HGF/SF on membrane K<sup>+</sup> currents and cell migration in MDCK II cells. HGF/SF activated membrane …