Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Ca-imaging"”.
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Development of microfluidic systems for studying functional connectivity between in vitro neuronal co-cultures
… individuals. This is highlighted during neurological disorders that can have a devastating impact on the sufferer's aptitude and quality of life. There is much which is not yet understood about what bhappens during neurological disorders including the changes which occur at a cellular level that …
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Characterisation of human enteroendocrine cells in organoid models
… satiety. EECs are specialised endocrine cells scattered throughout the gastrointestinal epithelium that release hormones in response to a wide range of luminal and systemic signals. This thesis focused on characterising the secretory mechanisms of three important gut hormones: glucagon-like …
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Characterising the functional homology of central nervous system drug targets in larval zebrafish (Danio rerio)
Pharmaceuticals are increasingly detected in aquatic environments at concentrations ranging from ng/L to mg/L, yet their potential impacts on non-target organisms remain poorly understood. Central nervous system (CNS)-targeting drugs are of particular concern because they are designed to act at low …
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Developing druggable in vitro models for investigating itch in atopic dermatitis
… sensation that drives a desire to scratch. It can induce severe skin damage and critically affect psychological wellbeing (e.g., sleep-deprivation, body-image insecurity). To investigate the burden of itch, a survey was conducted with ~2500 women within the general German population, where more …