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Showing 1 to 2 of 2 for “"CYP4F"”.
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Determination of Absolute Protein Content of Hepatic CYP4F Enzymes in Human Liver Microsomes Using LC/MS/MS Methodology and Comparison with Immunoquantification and Enzyme Activity
… donor human liver microsome (HLM) samples. The CYP4F subfamily of enzymes have recently been identified to be involved in the metabolism of endogenous compounds (arachidonic acid, leukotriene B4), nutrients (vitamin K1 and vitamin E), and xenobiotics (parfuramidine (DB289), DB1230, fingolimod). …
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Expression and Regulation of Human Cytochrome P450 4F Isoforms In Tissue Samples and Under Tnf-Alpha Challenges
<p>CYP4F (Cytochrome P4504F) enzymes metabolize endogenous molecules including leukotrienes, prostaglandins and arachidonic acid. The involvement of these endogenous compounds in inflammation has led to the hypothesis that changes in the inflamed tissue environment may affect the expression of …