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Showing 1 to 3 of 3 for “"CYP2D"”.

  1. CYP2D in the Brain Alters Response to Drugs and Neurotoxins

    Stocco, Marlaina Rosemaria2021

    Cytochrome P450 2D (CYP2D) is a subfamily of enzymes that metabolize many centrally acting drugs and neurotoxins. In humans, CYP2D6 is genetically polymorphic, resulting in variable activity. CYP2D in the liver is regulated primarily by genetics, while CYP2D in the brain is affected by genetics and …

    toronto-retro Repository record

  2. REPRESSION OF MULTIPLE CYP2D GENES IN MOUSE USING A SINGLE SIRNA CONSTRUCT

    Elraghy, Omaima

    clemson Repository record

  3. Effect of berberine on in vitro metabolism of sulfonylureas: a herb-drug interactions study

    Singh, A.Middlesex University2021

    … and tienilic acid as the inhibitors of CYP3A and CYP2D at 0.01 to 1.5 μM and 0.005 to 100 μM, respectively, with glyburide at 20 μM in 0.5 mg/mL microsomes and the NADPH regenerating system. The role of CYP2C in metabolism of gliclazide or glipizide was investigated by incubating these substrates …

    middlesex