Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"CYP genes"”.
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Transcriptional regulatory elements for basal expression and effects of phenobarbital and dexamethasone onmRNA levels of rabbit CYP2C genes
Cytochrome P450 (CYP) genes, expressed in many species, are involved in the oxidative metabolism of many xenobiotis as well as endogenous compounds. Expression of the rabbit CYP2C1 gene is observed only after induction with phenobarbital and is confined to the liver. The CYP2C2 gene is inducible in …
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Identification of Cyclophilin gene family in soybean and characterization of GmCYP1
I identified members of the Cyclophilin (CYP) gene family in soybean (Glycine max) and characterized the GmCYP1, one of the members of soybean CYP. CYPs belong to the immunophilin superfamily with peptidyl-prolyl cis-trans isomerase (PPIase) activity. PPIase catalyzes the interconversion of the …
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Comparative structural analysis of cytochrome P450 family CYP51 in the genus Cryptococcus
Cytochrome P450 monooxygenase CYP51 (sterol 14α-demethylase) is a well-known target of the azole drug fluconazole for treating cryptococcosis, a life-threatening fungal infection in immune-compromised patients in poor countries. Studies indicate that mutations in CYP51 confer fluconazole resistance …
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Developing novel systems for expression of intracellular membrane-bound human cytochrome P450 enzymes in baker’s yeast
Human cytochrome P450 (CYP) enzymes belong to a family of monooxygenase enzymes that are responsible for the metabolism, in a stereo-specific and stereo-selective manner, of diverse chemicals. These chemicals are often referred to as xenobiotics which are usually harmful and toxic to the human …
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Diversity and characterization of novel Cytochrome P450 2 genes in the marine teleost Fundulus Heteroclitus
The multiplicity and roles of cytochrome P450 CYP genes in the 2 family are not well known in fish. Characterizations of CYP2 genes were done in the killifish, Fundulus heteroclitus. Multiple cDNAs from three CYP2 subfamilies were isolated from killifish cDNA libraries. Sequence analyses showed …
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Identification and Characterization of Transcriptional Regulatory Elements for Liver-Specific Expression of Rabbit CYP2C Genes
… These enzymes are encoded by a superfamily of CYP genes, among which mammalian CYP2 is the largest family with a predominant liver-specific expression pattern. We have developed a functional analysis system using rabbit CYP2C 5$\sp\prime$ flanking region-luciferase chimeric constructs to …
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Studies on sweet corn: Stewart's wilt forecasting, the effect of maize dwarf mosaic on foliar diseases, and herbicide sensitivity
… eight foliar diseases, and the effect of hybrid CYP genotype on sweet corn yield following postemergence applications of mesotrione or nicosulfuron. Stewart’s disease can be forecasted using the Stevens, Stevens-Boewe, or Iowa State forecasts. These forecasts assume a high degree of host …