Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"CTD phosphorylation"”.
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DNA topology and Pol II CTD phosphorylation as stepwise regulators of chromatin architecture in differentiating human stem cells
… II activity is tuned by differentiation-specific phosphorylation of its C-terminal domain (CTD), which modulates interactions with co-transcriptional regulators and condensates. These mechanisms likely intersect: phosphorylated Pol II may be recruited to negatively supercoiled or secondary …
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Mechanisms of recruitment of the CTD phosphatase Rtr1 to RNA polymerase II
The C-terminal domain (CTD) of the RNA polymerase II (RNAPII) subunit Rpb1 must exist in a hypophosphorylated state prior to forming a competent transcription initiation complex. However, during transcription, specific kinases and phosphatases act on the RNAPII CTD to regulate its phosphorylation …
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RNA Polymerase II control in the changing transcriptional landscape
… RPB1, has a conserved C-terminal repeat domain (CTD) that contains 52 heptapeptide repeats and functions as a scaffold where transcription regulators bind. This unstructured 'tail' undergoes phosphorylation changes during the transcription cycle, modifying its interaction with associated proteins …
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Investigations into the regulation of histone H2B monoubiquitination
Transkriptionsassoziierte Chromatinmodifikationen spielen eine wichtige Rolle bei der Reglation der Genexpression. So konnte die Mono-Ubiquitinierung des Lysinrestes K120 von Histon H2B (H2Bub1) beispielsweise mit transkriptionell aktiven Genen in Verbindung gebracht werden. Zum einen konnte …