Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"CRMP2"”.
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Interplay between collapsin response mediator protein 2 (CRMP2) phosphorylation and sumoylation modulates NaV1.7 trafficking
… axonal collapsin response mediator protein 2 (CRMP2) by small ubiquitin-like modifier (SUMO) and phosphorylation could affect Nav trafficking and function. Expression of a CRMP2 SUMOylation incompetent mutant (CRMP2-K374A) in neuronal model CAD cells, which express predominantly Nav1.7 …
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A Novel Collapsing Response Mediator Protein 2 Binding Domain for Kinesin Light Chain 3
… In this study, we investigated the expression of CRMP2 in mouse testis and we studied if CRMP2 and KLC3 interact. We observed CRMP2 mRNA expression in testis, along with expression of the other family members CRMP1, CRMP3 and CRMP4. CRMP2 protein localized in elongating spermatids to the neck …
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Reassessing the role of Cyclin-dependent kinase 5 in tumourigenesis
… in cell lines and intact tissue, tau and CRMP2 were confirmed as Cdk5 targets. Subsequently, a panel of total and phospho-specific antibodies to each substrate was assessed for compatibility with the immunohistochemistry protocol to serve as a surrogate for examining Cdk5 activity in …
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The role of semaphorin 3A signaling underlying learning and memory formation in the postnatal mouse brain
… altering collapsin response mediator protein 2 (CRMP2). Sema3A signaling has been studied extensively in the developing nervous system, though much less is known about its role in the adult brain. Specifically with respect to spatial learning, brain areas including the hippocampus and regions of …
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Circulating Autoantibodies In Human Traumatic Spinal Cord Injury Subjects and Their Relationship to The Development of Neuropathic Pain
… (GFAP) and collapsin response mediator protein2 (CRMP2) were identified as candidate autoantigens. The hypothesis is that proteins from the injured spinal cord released by SCI trigger autoantibody production which can lead to the development of NP.</p> <p><strong>Results:</strong></p> <p>The …