"CRISPR base editor" · 2 results · Global ETD Search

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Showing 1 to 2 of 2 for “"CRISPR base editor"”.

Understanding information at the biomolecular level using statistics and machine learning

Luu, Alan M.University of Illinois at Urbana-Champaign2022

Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms

uiuc Repository record for Understanding information at the biomolecular level using statistics and machine learning (opens in a new tab)
Functional assessment of BRAF and CRAF through Base Editor 3 mutagenesis reveals residues and regions critical for ERK1/2 signalling

Cook, FrazerUniversity of Cambridge2024

… drive paradoxical activation of wild-type RAF. Base editor 3 (BE3) is a gene editing tool comprised of a nickase Cas9 fused to a cytidine deaminase and a uracil DNA glycosylase inhibitor. This can be used to generate high-efficiency C to T mutations. This thesis describes the use of a high …

cambridge Repository record for Functional assessment of BRAF and CRAF through Base Editor 3 mutagenesis reveals residues and regions critical for ERK1/2 signalling (opens in a new tab)