Global ETD Search
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Showing 1 to 2 of 2 for “"CRISPLD2"”.
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Gene Discovery In Nonsyndromic Cleft Lip With Or Without Cleft Palate
… 0.001≤p≤0.005), Wnt11 (2 SNPs, 0.001≤p≤0.01) and CRISPLD2 (4 SNPs, 0.001≤p<0.05). The most interesting findings were for CRISPLD2. This gene is expressed in the fused mouse palate at E17.5. In zebrafish, crispld2 localized to the craniofacial region by one day post fertilization. Morpholino …
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Genetic Pathway Analysis of Abnormal Facial Development In Nonsyndromic Cleft Lip and Palate
… datasets. The second gene, identified in the CRISPLD2 network, was found to play a novel role in regulating oral and facial development, with perturbation causing abnormal oral morphogenesis in zebrafish. The final study used bioinformatic, cell-based and transgenic zebrafish approaches …