Global ETD Search

Characterizing interactions between cAMP responsive element binding protein 1 and methyl-CpG-binding protein 2 as a potential transcriptional activation complex

Martinez, EsmeraldaThe University of Texas Medical Branch at Galveston2018

… to cAMP responsive element binding protein (CREB1) to facilitate this action. This hypothesis is under-studied biochemically, and this project aims to elucidate biochemical and biophysical information to further understand this potential interaction. In this project, we qualitatively study …

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Impairment of cAMP/PKA/CREB1 signaling in skeletal muscle drives metabolic dysfunction in cancer cachexia: The key role of PDE4D, a cAMP-hydrolyzing phosphodiesterase

Graziani, Andrea, Bodo, LorenzaUniversità degli Studi di Torino2026

unito Repository record for Impairment of cAMP/PKA/CREB1 signaling in skeletal muscle drives metabolic dysfunction in cancer cachexia: The key role of PDE4D, a cAMP-hydrolyzing phosphodiesterase (opens in a new tab)

Role of Synapsin In Long-Term Synaptic Facilitation In Aplysia

Hart, Anne2011

… cAMP response element-binding protein-1 (CREB1) mediates the 5-HT-induced regulation of synapsin. Results from Chromatin Immunoprecipitation (ChIP) assays indicated that 5-HT treatment enhanced association of CREB1 surrounding the CRE site in the <em>synapsin</em> promoter and led to …

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Small Molecules Modulate Chromatin Accessibility to Promote NEUROG2-Mediated Fibroblast-to-Neuron Reprogramming

Smith, Derek Kurtis2018

… of FD. These small molecules promote NEUROG2 and CREB1 co-transcription, induce SOX4 expression, and promote SOX4-dependent chromatin remodeling. Genome-wide occupancy analysis revealed that SOX4 targets numerous SWI/SNF complex subunits and co-binds with NEUROG2 to enhance the expression of …

utswmed Repository record for Small Molecules Modulate Chromatin Accessibility to Promote NEUROG2-Mediated Fibroblast-to-Neuron Reprogramming (opens in a new tab)

Novel Small-RNA Mediated Gene Regulatory Mechanisms for Long-Term Memory

Rajasethupathy, Priyamvada2012

… through regulation of the transcriptional factor CREB1 and translation factor CPEB respectively. We therefore provide the first evidence that a modulatory neurotransmitter important for learning can regulate the levels of small RNAs and present a novel role for miR-124 and miR-22 in long-term …

columbia-diss Repository record for Novel Small-RNA Mediated Gene Regulatory Mechanisms for Long-Term Memory (opens in a new tab)

Identification and Targeting of Downstream Ar-Camkk2-Mediated Mechanisms For The Treatment of Advanced Prostate Cancer

Lin, Chenchu, <p><a href="https://orcid.org/0000-0002-7163-2035" target="_blank">https://orcid.org/0000-0002-7163-2035</a></p>2022

… redundancy between two CREB family members, CREB1 and Activating Transcription Factor 1. Deletion of both genes impaired transcriptional activity and maximal prostate cancer cell proliferation in tissue culture and tumor initiation as well as growth in CRPC. Therapeutically, pharmacological …

uthsc Repository record for Identification and Targeting of Downstream Ar-Camkk2-Mediated Mechanisms For The Treatment of Advanced Prostate Cancer (opens in a new tab)