Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"CRC susceptibility"”.
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Rare Variant Association Studies In Crohn’S Disease and Colorectal Cancer: Methods and Applications
… of Crohn’s disease and colorectal cancer (CRC) risk. Patients with Crohn’s disease, a condition that causes chronic inflammation of the gastrointestinal tract, are at increased risk of colorectal cancer morbidity and mortality. Genome-wide association studies using single marker approaches …
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Common genetic variance at the SMAD9 colorectal cancer risk locus influences tumour mutational phenotype
… variance associated with colorectal cancer (CRC) risk can influence the somatic mutational landscapes of CRC. Some Mendelian cancer syndromes, such as Lynch syndrome (LS) and MUTYH associated polyposis, associate with defined mutational landscapes and this association can be functionally …