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Showing 1 to 1 of 1 for “"CRC predisposition"”.

  1. Germline variants associated with alternative splicing in colonic mucosa

    The heritability of colorectal cancer (CRC) has been estimated between 7.4% and 26% from a range of analyses based on family lineages and genetic similarity. Certain rare, high penetrance variants are well characterized, though these are estimated to account for only ~5% of all CRC cases. The …

    edinburgh Repository record for Germline variants associated with alternative splicing in colonic mucosa (opens in a new tab)